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142851-03-4

N-Boc-4-Carbethoxy Piperidine

CAS: 142851-03-4

Molecular Formula: C13H23NO4

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142851-03-4 - Names and Identifiers

Name N-Boc-4-Carbethoxy Piperidine
Synonyms N-Boc-4-Carbethoxy Piperidine
N-BOC-4-CARBETHOXY PIPERIDINE
Ethyl N-Boc-piperidine-4-carboxylate
N-BOC-4-piperidine forMic acid ethyl ester
Tert-Butyl Ethyl Piperidine-1,4-Dicarboxylate
1-BOC-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
1-TERT-BUTYL 4-ETHYL 1,4-PIPERIDINEDICARBOXYLATE
1-TERT-BUTYL 4-ETHYL PIPERIDINE-1,4-DICARBOXYLATE
1-tert-butyl 4-ethyl piperidine-1,4-dicarboxylate
Ethyl 1-tert-butoxycarbonylpiperidine-4-carboxylate
Dimethylethyl Piperidinedicarboxylic Acid Ethyl Ester
1-(tert-butoxycarbonyl)-4-ethylpiperidine-4-carboxylic acid
1-(TERT-BUTYL) 4-ETHYL TETRAHYDRO-1,4(2H)-PYRIDINEDICARBOXYLATE
PIPERIDINE-1,4-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-ETHYL ESTER
CAS 142851-03-4
InChI InChI=1/C13H23NO4/c1-5-13(10(15)16)6-8-14(9-7-13)11(17)18-12(2,3)4/h5-9H2,1-4H3,(H,15,16)
InChIKey MYHJCTUTPIKNAT-UHFFFAOYSA-N

142851-03-4 - Physico-chemical Properties

Molecular FormulaC13H23NO4
Molar Mass257.33
Density1.046 g/mL at 25 °C
Boling Point120-135 °C/0.5 mmHg
Flash Point>230°F
Solubility Chloroform, Ethyl Acetate
Vapor Presure0mmHg at 25°C
AppearanceLiquid
ColorClear colorless to pale yellow
pKa-2.23±0.40(Predicted)
Storage ConditionInert atmosphere,2-8°C
Refractive Indexn20/D 1.458

142851-03-4 - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk CodesR22 - Harmful if swallowed
R37/38 - Irritating to respiratory system and skin.
R41 - Risk of serious damage to eyes
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
WGK Germany3
HS Code29333990
Hazard ClassIRRITANT

142851-03-4 - Reference Information

introduction ethyl N-Boc-4-piperidine formate has an extremely light yellow or light yellow liquid appearance at normal temperature and pressure and can be used as an intermediate in organic synthesis. It is a commercial organic synthon, which has good solubility in common organic solvents such as ethyl acetate, dichloromethane, and chloroform, and poor solubility in water.
Use Ethyl N-Boc-4-piperidinoate is a common organic synthesis intermediate. Its main use is to participate in the synthesis of drug molecules and biologically active molecules as a molecular skeleton. The ester group on the ring of ethyl N-Boc-4-piperidinoate can be converted into a series of active functional groups, such as hydroxyl, aldehyde, etc. The N-Boc group on the other side can easily remove Boc and release the secondary amine. In addition, the N-Boc can also reduce the Boc group to methyl group under the reduction of lithium tetrahydroaluminum, so as to obtain the corresponding Tertiary amine compounds.
synthesis method aiming at the synthesis of ethyl N-Boc-4-piperidinoate, the conventional synthesis method is to obtain Boc-protected ethyl 4-piperidinoate by reacting with ditert-butyl dicarbonate starting from commercial ethyl 4-piperidinoate. There are literatures that the target product can be obtained by directly stirring the two reactions together, and there are also related literatures that the reaction process is iodized and acetonitrile is used as a solvent to obtain the target product in a high yield.
Last Update:2024-04-09 20:52:54
142851-03-4
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Product Name: Ethyl N-Boc-piperidine-4-carboxylate Visit Supplier Webpage Request for quotation
CAS: 142851-03-4
Tel: +86-18821248368
Email: Int06@meryer.com
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Product Name: EthylN-Boc-piperidine-4-carboxylate Request for quotation
CAS: 142851-03-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
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Changsha Changtang import and Export Co., Ltd.
Product Name: N-Boc-4-Carbethoxy Piperidine Request for quotation
CAS: 142851-03-4
Tel: +86 18942506900
Email: lilyqu@chemoway.com
Mobile: +86 18942506900
QQ: 3182628472 Click to send a QQ message
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WhatsApp: +86 18942506900
Linkedin: +86 18942506900
Suzhou Haofan biological Co., Ltd.
Product Name: Ethyl N-Boc-piperidine-4-carboxylate Request for quotation
CAS: 142851-03-4
Tel: +86 0512-69209928
Email: wuhao@highfine.com
     merry@highfine.com
     chenmengqi@highfine.com
QQ: 4006286883 Click to send a QQ message
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: Ethyl N-Boc-piperidine-4-carboxylate Visit Supplier Webpage Request for quotation
CAS: 142851-03-4
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Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
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Product Name: Ethyl-N-BOC-piperidine-4-carboxylate Visit Supplier Webpage Request for quotation
CAS: 142851-03-4
Tel: +86 0571-86722205
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142851-03-4
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