143722-25-2

143722-25-2 - Names and Identifiers

Name	[2-[2-(TriPhenylMethyl)-2H-tetrazol-5-YL]phenyl]boronic acid
Synonyms	(1-Trityl-1H-tetrazol-5-yl)phenylboronic acid 2-(2-TRITYL-2H-TETRAZOL-5-YL)PHENYLBORONIC ACID 2-(2-Trityl-2H-tetrazol-5-YL)phenylboronic acid 2-(1-Trityl-1H-tetrazol-5-yl)phenylboronic acid [2-(1-trityl-1H-tetrazol-5-yl)phenyl]boronic acid 2-[2-(triphenylmethyl)-2H-trtrazol-5-yl]phenylboronicacid [2-[2-(TRIPHENYLMETHYL)-2H-TETRAZOL-5-YL]PHENYL]BORONIC ACID [2-[2-(TriPhenylMethyl)-2H-tetrazol-5-YL]phenyl]boronic acid B-[2-[2-(TriphenylMethyl)-2H-tetrazol-5-yl]phenyl]boronic Acid Boronic acid,B-[2-[2-(triphenylmethyl)-2H-tetrazol-5-yl]phenyl]-
CAS	143722-25-2
InChI	InChI=1/C26H21BN4O2/c32-27(33)24-19-11-10-18-23(24)25-28-29-30-31(25)26(20-12-4-1-5-13-20,21-14-6-2-7-15-21)22-16-8-3-9-17-22/h1-19,32-33H

143722-25-2 - Physico-chemical Properties

Molecular Formula	C26H21BN4O2
Molar Mass	432.28
Density	1.20
Melting Point	146-149°C (dec.)
Boling Point	685.2±65.0 °C(Predicted)
Flash Point	368.2°C
Solubility	DMSO (Sparingly), Methanol (Slightly)
Vapor Presure	1.03E-19mmHg at 25°C
Appearance	Solid
Color	White
pKa	7.97±0.58(Predicted)
Storage Condition	Refrigerator
Refractive Index	1.645

143722-25-2 - Risk and Safety

Hazard Class

IRRITANT

143722-25-2 - Introduction

[2-[2-(TriPhenylMethyl)-2H-tetrazol-5-YL]phenyl]boronic acid, also known as TPAB, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: TPAB is a white solid.
-Solubility: TPAB has good solubility in organic solvents.
-Stability: TPAB is relatively stable under dry conditions.

Use:
One of the main uses of TPAB is as a catalyst for organic synthesis reactions. It can be used for Phenylboronic acid coupling reaction, C- H bond activation reaction and cyclization reaction. In addition, TPAB can also be used in other organic synthesis reactions, for the synthesis of functional compounds, drugs and dyes.

Method:
The preparation method of TPAB is relatively complicated, and a commonly used method is to prepare by chemical synthesis. Firstly, Phenylboronic acid is reacted with 1-trityl -1H-Tetrazole under appropriate conditions, and then the pure TPAB product is obtained through the steps of crystallization, filtration and drying.

Safety Information:
when using TPAB, you need to pay attention to the following safety precautions:
- TPAB may be eye and skin irritant, avoid contact with skin and eyes.
-During use, care should be taken to avoid inhalation or intake of the compound.
-Wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing during operation.
-During storage and disposal, operations should be carried out in accordance with relevant safety regulations to avoid environmental pollution.

Last Update：2024-04-09 21:01:54