145413-17-8
(4'-Butyl[1,1'-biphenyl]-4-yl)-boronic acid
CAS: 145413-17-8
Molecular Formula: C16H19BO2
145413-17-8 - Names and Identifiers
145413-17-8 - Physico-chemical Properties
| Molecular Formula | C16H19BO2 |
| Molar Mass | 254.13 |
| Density | 1.09 |
| Melting Point | 157℃ |
| Boling Point | 424.7±48.0 °C(Predicted) |
| pKa | 8.61±0.17(Predicted) |
| Storage Condition | 2-8°C |
145413-17-8 - Introduction
(4 '-Butyl[1,1'-biphenyl]-4-yl)-boronic acid is an organic compound with the chemical formula C16H19BO2. It is a white to light yellow crystalline solid, soluble in organic solvents such as ethanol, chloroform and dimethylformamide.
(4 '-Butyl[1,1'-biphenyl]-4-yl)-boronic acid is often used as a reagent in organic synthesis. It can be used as a ligand of copper catalyst for the synthesis of various compounds. In addition, it is also commonly used in the field of organic chemistry for research and synthesis of air-sensitive ligands.
The preparation of (4 '-Butyl[1,1'-biphenyl]-4-yl)-boronic acid can be carried out by the following steps: First, nitrosobenzene reacts to generate biphenyl. The biphenyl and alcohol dehydrating agent then react to form the corresponding phenol. Finally, the phenol is reacted with an alkyl halide to produce 4-butyl biphenyl by dehalogenation. Finally, a substitution reaction using boric acid and a base yields (4 '-Butyl[1,1'-biphenyl]-4-yl)-boronic acid.
In terms of safety,(4 '-Butyl[1,1'-biphenyl]-4-yl)-boronic acid is irritating and corrosive. Appropriate personal protective equipment such as lab gloves, goggles and protective clothing is required for operation. At the same time, contact with skin, eyes and respiratory tract should be avoided. Use to maintain good ventilation, and comply with safety procedures.
(4 '-Butyl[1,1'-biphenyl]-4-yl)-boronic acid is often used as a reagent in organic synthesis. It can be used as a ligand of copper catalyst for the synthesis of various compounds. In addition, it is also commonly used in the field of organic chemistry for research and synthesis of air-sensitive ligands.
The preparation of (4 '-Butyl[1,1'-biphenyl]-4-yl)-boronic acid can be carried out by the following steps: First, nitrosobenzene reacts to generate biphenyl. The biphenyl and alcohol dehydrating agent then react to form the corresponding phenol. Finally, the phenol is reacted with an alkyl halide to produce 4-butyl biphenyl by dehalogenation. Finally, a substitution reaction using boric acid and a base yields (4 '-Butyl[1,1'-biphenyl]-4-yl)-boronic acid.
In terms of safety,(4 '-Butyl[1,1'-biphenyl]-4-yl)-boronic acid is irritating and corrosive. Appropriate personal protective equipment such as lab gloves, goggles and protective clothing is required for operation. At the same time, contact with skin, eyes and respiratory tract should be avoided. Use to maintain good ventilation, and comply with safety procedures.
Last Update：2024-04-10 22:29:15
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Spot supply
Product Name: (4'-Butyl-[1,1'-biphenyl]-4-yl)boronicacid Request for quotationCAS: 145413-17-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Product Name: (4'-Butyl[1,1'-biphenyl]-4-yl)-boronic acid Visit Supplier Webpage Request for quotation
CAS: 145413-17-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 145413-17-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
145413-17-8
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