147086-81-5

147086-81-5 - Names and Identifiers

Name	trans-(4S,6S)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol, 7,7-dioxide
Synonyms	Dorzolamide inter-7 DorzolaMide inter-7 (4S,6S)-5,6-Dihydro-4-hydroxy- 4H-THIENO[2,3-B]THIOPYRAN-4-OL (4S,6S)-6-Methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol (4S,6S)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol 7,7-dioxide (4S,6S)-5,6-DIHYDRO-6-METHYL-4H-THIENO[2,3-B]THIOPYRAN-4-OL 7,7-DIOXIDE (4S,6S)-5,6-Dihydro-4-hydroxy-6-methylthieno[2,3-b]thiopyran-7,7-dioxide (4S,6S)-5,6-Dihydro-4-hydroxy-6-Methylthieno[2,3-b]thiopyran-7,7-dioxide trans-(4S,6S)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol, 7,7-dioxide
CAS	147086-81-5
EINECS	417-290-3
InChI	InChI=1/C8H10O3S2/c1-5-4-7(9)6-2-3-12-8(6)13(5,10)11/h2-3,5,8-9H,4H2,1H3/t5-,8?/m0/s1

147086-81-5 - Physico-chemical Properties

Molecular Formula	C8H10O3S2
Molar Mass	218.29
Density	1.462±0.06 g/cm3(Predicted)
Boling Point	433.3±45.0 °C(Predicted)
pKa	13.06±0.40(Predicted)
Storage Condition	2-8°C
Refractive Index	1.66

147086-81-5 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
Safety Description	36 - Wear suitable protective clothing.

147086-81-5 - Introduction

trans-(4S,6S)-5, [2,3-b]thiopyran-4-ol is an organic compound containing thiophene and thiopyran. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White solid
-Molecular formula: C9H7O3S2
-Molecular weight: 231.29g/mol
-Melting point: 220-222 ° C
-Boiling point: not applicable, it will decompose at this temperature
-Solubility: Slightly soluble in water, soluble in some organic solvents such as dimethyl sulfoxide and dimethylformamide

Use:
-As an intermediate in organic synthesis, it can be used to synthesize other organic compounds
-Has potential application value in the field of drugs and pesticides, and can be used as a part of the active skeleton of drugs

Method:
trans-(4S,6S)-5, [2,3-b]thiopyran-4-ol, the preparation method of 7,7-dioxide is complicated and generally requires multi-step synthesis. The following is a possible procedure:
1.4-methyl thieno [2,3-b] thiopyran was synthesized by alkylation of thiophene and thiopyran.
2. In the presence of an oxidizing agent, dilute hydrochloric acid and hydrogen peroxide are used for oxidation to obtain the desired dioxide product.

Safety Information:
- trans-(4S)-5, [2,3-b]thiopyran-4-ol, 7,7-dioxide has limited safety data, so it should be used with caution.
-Follow laboratory safety practices and wear appropriate personal protective equipment, such as lab gloves and eye protection.
-Due to the lack of sufficient safety data, the toxicity and environmental impact of this compound on the human body are not clear, so it needs to be handled and stored carefully to avoid harm to the human body and the environment.

Last Update：2024-04-09 21:04:16