147699-19-2

147699-19-2 - Names and Identifiers

Name	1-Piperidinecarboxylic acid, 4-[2-[(methylsulfonyl)oxy]ethyl]-,1,1-dimethylethyl ester
Synonyms	1-N-Boc-4-(2-Methanesulfonyloxyethyl)piperidine 1-BOC-4-(2-METHANESULFONYLOXY-ETHYL)-PIPERIDINE tert-Butyl 4-(2-(methylsulfonyloxy)ethl)piperidine-1-carboxylate tert-butyl 4-[2-(methanesulfonyloxy)ethyl]piperidine-1-carboxylate tert-butyl 4-(2-((methylsulfonyl)oxy)ethyl)piperidine-1-carboxylate tert-butyl 4-{2-[(methylsulfonyl)oxy]ethyl}-1-piperidinecarboxylate 4-(2-methylsulfonyloxyethyl)-1-piperidinecarboxylic acid tert-butyl ester 1-Piperidinecarboxylic acid, 4-[2-[(methylsulfonyl)oxy]ethyl]-,1,1-dimethylethyl ester
CAS	147699-19-2

147699-19-2 - Physico-chemical Properties

Molecular Formula	C13H25NO5S
Molar Mass	307.41
Density	1.154±0.06 g/cm3(Predicted)
Boling Point	431.1±18.0 °C(Predicted)
pKa	-1.54±0.40(Predicted)
Storage Condition	2-8°C

147699-19-2 - Introduction

1-Piperidinecarboxylic acid, 4-[2-[(methylsulfonyl)oxy]ethyl]-,1,1-dimethylethyl ester is an organic compound with the following properties:
-Appearance is white or off-white crystal
-Soluble in organic solvents such as methanol, dimethylformamide, insoluble in water
-is a p-methylbenzenesulfonyl-protected β-Hydroxyethyl piperidine derivative

1-Piperidinecarboxylic acid, 4-[2-[(methylsulfonyl)oxy]ethyl]-,1,1-dimethylethyl ester is mainly used as an intermediate in chemical reactions in organic synthesis, commonly used in the synthesis of drugs, bioactive small molecules and heterocyclic compounds. It can be used as a strong base reagent to participate in nucleophilic substitution reactions, esterification reactions and electrophilic addition reactions.

The preparation of the compound is generally carried out by the following steps:
First, β-Hydroxyethyl piperidine is reacted with tert-butoxycarbonyl (Boc) to form the Boc protection of β-Hydroxyethyl piperidine. Then, by reacting with methylbenzenesulfonyl chloride, a methanesulfonyl group is introduced. Finally, the Boc protecting group was removed by acidolysis of the carbonate to give the final product 1-Piperidinecarboxylic acid, 4-[2-[(methylsulfonyl)oxy]ethyl]-,1,1-dimethylethyl ester.

Regarding safety information, 1-Piperidinecarboxylic acid, 4-[2-[(methylsulfonyl)oxy]ethyl]-,1,1-dimethylethyl ester is relatively stable under normal operating conditions, but should pay attention to the following safety matters:
-Avoid contact with strong oxidants, avoid fire sources and open flames.
-During use, it is recommended to wear work gloves, protective glasses and protective mask to ensure good ventilation.
-Avoid direct sunlight and high temperature environment when storing, and keep the container sealed.
-Read the safety data sheet of the product before use and follow the correct operating steps. If necessary, consult a chemical expert for safe use recommendations.

Last Update：2024-04-09 21:01:54