148231-12-3
5,8-dibromo-Quinoxaline
CAS: 148231-12-3
Molecular Formula: C8H4Br2N2
148231-12-3 - Names and Identifiers
| Name | 5,8-dibromo-Quinoxaline |
| Synonyms | 8-DibroMoquinoxaline 5,8-Dibromoquinoxaline 5,8-DibroMoquinoxaline 5,8-dibromo-Quinoxaline Quinoxaline, 5,8-dibromo- Quinoxaline, 5,8-dibroMo- |
| CAS | 148231-12-3 |
148231-12-3 - Physico-chemical Properties
| Molecular Formula | C8H4Br2N2 |
| Molar Mass | 287.94 |
| Density | 2.022±0.06 g/cm3(Predicted) |
| Melting Point | 198-203°C (dec.) |
| Boling Point | 352.5±37.0 °C(Predicted) |
| pKa | -2.28±0.30(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
148231-12-3 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 2811 |
| WGK Germany | 3 |
| Hazard Class | 6.1 |
| Packing Group | Ⅲ |
148231-12-3 - Introduction
5,8-Dibromo-quinoxaline is an organic compound with a specific structure. Its molecular formula is C12H6Br2N2, and its structure contains two bromine atoms and a pyrazine ring.
Regarding the properties of 5,8-dibromo-quinoxaline, it is a solid with white crystals. It has a melting point of 220-222 degrees Celsius and a boiling point of about 470 degrees Celsius. It is insoluble in water at normal temperature, but soluble in organic solvents such as alcohols, ethers and ketones.
This compound has some use in medical research. It is used as an intermediate in the synthesis of certain anticancer drugs in the pharmaceutical field. In addition, 5,8-dibromo-quinoxaline may also be used in the preparation of organic optoelectronic devices and other fields.
Regarding the production method, 5,8-dibromo-quinoxaline can be produced by a multi-step synthesis method. A common method is the condensation of 2,5-dibromopyrazine and O-dinitrobenzene, followed by a cyclization reaction to produce the target product.
When using 5,8-dibromo-quinoxaline, you need to pay attention to its safety. It can be irritating to the eyes, skin and respiratory system, so it is necessary to take appropriate protective measures, such as wearing glasses and gloves, to avoid inhaling its gas or contact with skin. In addition, during storage and handling, contact with strong oxidants and strong acids should be avoided to prevent dangerous reactions.
Regarding the properties of 5,8-dibromo-quinoxaline, it is a solid with white crystals. It has a melting point of 220-222 degrees Celsius and a boiling point of about 470 degrees Celsius. It is insoluble in water at normal temperature, but soluble in organic solvents such as alcohols, ethers and ketones.
This compound has some use in medical research. It is used as an intermediate in the synthesis of certain anticancer drugs in the pharmaceutical field. In addition, 5,8-dibromo-quinoxaline may also be used in the preparation of organic optoelectronic devices and other fields.
Regarding the production method, 5,8-dibromo-quinoxaline can be produced by a multi-step synthesis method. A common method is the condensation of 2,5-dibromopyrazine and O-dinitrobenzene, followed by a cyclization reaction to produce the target product.
When using 5,8-dibromo-quinoxaline, you need to pay attention to its safety. It can be irritating to the eyes, skin and respiratory system, so it is necessary to take appropriate protective measures, such as wearing glasses and gloves, to avoid inhaling its gas or contact with skin. In addition, during storage and handling, contact with strong oxidants and strong acids should be avoided to prevent dangerous reactions.
Last Update：2024-04-09 21:54:55
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