150725-87-4
Ro 46-2005
CAS: 150725-87-4
Molecular Formula: C23H27N3O6S
150725-87-4 - Names and Identifiers
| Name | Ro 46-2005 |
| Synonyms | RO462005 RO 462005 RO-462005 Ro 46-2005 Benzenesulfonamide,4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(3-methoxyphenoxy)-4-pyrimidinyl]- |
| CAS | 150725-87-4 |
150725-87-4 - Physico-chemical Properties
| Molecular Formula | C23H27N3O6S |
| Molar Mass | 473.54 |
| Density | 1.299±0.06 g/cm3(Predicted) |
| Boling Point | 617.5±65.0 °C(Predicted) |
| Solubility | DMSO: ≥ 28 mg/mL |
| pKa | 0.83±0.10(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
150725-87-4 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.112 ml | 10.559 ml | 21.117 ml |
| 5 mM | 0.422 ml | 2.112 ml | 4.223 ml |
| 10 mM | 0.211 ml | 1.056 ml | 2.112 ml |
| 5 mM | 0.042 ml | 0.211 ml | 0.422 ml |
Last Update：2024-01-02 23:10:35
150725-87-4 - Reference Information
| biological activity | Ro 46-2005 is a new non-peptide endothelin antagonist that inhibits human vascular smooth muscle cells (ETA receptor) with IC50 of 220 nM respectively. |
Last Update：2024-04-10 22:29:15
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