ChemBK
  • Home
  • Product Category

1538-75-6

Trimethylacetic anhydride

CAS: 1538-75-6

Molecular Formula: C10H18O3

  1. Home
  2. Product Category
  3. Organic raw materials
  4. carboxylic acid
  5. 1538-75-6

1538-75-6 - Names and Identifiers

Name Trimethylacetic anhydride
Synonyms Pivalic anhydride
Bis(pivalic)anhydride
Trimethylacetic anhydride
Bis(pivalic acid)anhydride
BIS(TRIMETHYLACETIC) ANHYDRIDE
2,2-dimethylpropanoic anhydride
2,2-DIMETHYLPROPIONIC ANHYDRIDE
Bis(2,2-dimethylpropionic)anhydride
2,2-DIMETHYLPROPIONIC ACID ANHYDRIDE
Bis(2,2-dimethylpropionic acid)anhydride
2,2-Dimethylpropionic anhydride, Pivalic anhydride
CAS 1538-75-6
EINECS 216-263-1
InChI InChI=1/C10H18O3/c1-9(2,3)7(11)13-8(12)10(4,5)6/h1-6H3

1538-75-6 - Physico-chemical Properties

Molecular FormulaC10H18O3
Molar Mass186.25
Density0.918g/mLat 25°C(lit.)
Boling Point193°C(lit.)
Flash Point135°F
Solubility Miscible with acetonitrile.
Vapor Presure62.1Pa at 25℃
AppearanceLiquid
ColorClear colorless
BRN386552
Storage ConditionInert atmosphere,Room Temperature
SensitiveMoisture Sensitive
Refractive Indexn20/D 1.409(lit.)

1538-75-6 - Risk and Safety

Hazard SymbolsC - Corrosive
Corrosive
Risk Codes34 - Causes burns
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDsUN 2920 8/PG 2
WGK Germany3
FLUKA BRAND F CODES9-13-21
TSCAYes
HS Code29159000
Hazard Class8
Packing GroupII

1538-75-6 - Reference Information

LogP2.15
EPA chemical substance information information provided by: ofmpeb.epa.gov (external link)
uses pivalic anhydride is a metabolite of the dual prodrug of ganciclovir (6-dgc V-dpiv).
synthetic use trimethylacetic anhydride is used as an acylating and esterifying agent, which participates in acylation and esterification reactions with aniline and phenol. Trimethylacetic anhydride is also used for solid-phase oligonucleotide synthesis and kinetic resolution of racemic 2-hydroxy-γ-butyrolactone and diphenylacetic acid for the production of cyano-4, N-tert-butoxycarbonyl piperidine, it is also used in solid-phase oligonucleotide synthesis.
preparation currently, the synthesis of trimethyl acetic anhydride from pivalic acid is mainly realized by dehydrating agent or under the action of acetic anhydride. This method requires the use of dehydrating agents with serious environmental pollution, and has a long production process route, many processes, high investment in equipment and capital construction, and high requirements for corrosion resistance of the equipment. If the exchange dehydration reaction is carried out with acetic anhydride, a longer reaction time is required. It is of great significance to systematically study the preparation process of trimethyl acetic anhydride. The synthesis reaction formula of trimethyl acetic anhydride is shown below: Fig. 1
Last Update：2024-04-09 02:00:04
1538-75-6
Supplier List
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Trimethylacetic anhydride Visit Supplier Webpage Request for quotation
CAS: 1538-75-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
Spot supply
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Trimethylacetic anhydride Visit Supplier Webpage Request for quotation
CAS: 1538-75-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Trimethylacetic anhydride Visit Supplier Webpage Request for quotation
CAS: 1538-75-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Zouping Mingxing Chemical Co., Ltd.
Product Name:  Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987 Click to send a QQ message
WhatsApp: 13605431940
Handan Huajun Chemicals Co.,Ltd
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel:
Email: hdhjchem@yeah.net
Mobile: 18630058311
QQ: 573631441 Click to send a QQ messageSend QQ message
Shanghai Macklin Biochemical Co., Ltd
Featured ProductsSpot supply
Product Name: Trimethylacetic anhydride Visit Supplier Webpage Request for quotation
CAS: 1538-75-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
CHEMBSF (Shanghai) Biomedical Technology Co., Ltd
Spot supply
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 021-60556179
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Jiangsu Pules Biotechnology Co.,Ltd.
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 0513-66814854
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Shanghai Amole Biotechnology Co., Ltd.
Spot supply
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365 Click to send a QQ message
Wechat: 18916960931
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: Trimethylacetic anhydride Visit Supplier Webpage Request for quotation
CAS: 1538-75-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
SKYRUN INDUSTRIAL CO.,LTD
Spot supply
Product Name: Trimethylacetic anhydride Visit Supplier Webpage Request for quotation
CAS: 1538-75-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185 Click to send a QQ messageSend QQ message
Wechat: chinaskyrun
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Zouping Mingxing Chemical Co., Ltd.
Product Name:  Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987 Click to send a QQ message
WhatsApp: 13605431940
Handan Huajun Chemicals Co.,Ltd
Product Name: Trimethylacetic anhydride Request for quotation
CAS: 1538-75-6
Tel:
Email: hdhjchem@yeah.net
Mobile: 18630058311
QQ: 573631441 Click to send a QQ messageSend QQ message
View History
1538-75-6
32195-55-4
卡波普
3989-75-1
Nelfinavir mesylate
Emapunil(AC-5216)
还原黄 2
EMIM DCA
  • Home
  • Product Category

© 2015, 2023 ChemBK.com All Rights Reserved | Build: 20230617001