1540426-95-6

1540426-95-6 - Names and Identifiers

Name	rosuvastatin intermediates C-4
Synonyms	Rosuvastatin calciuM-C4 Rosuvastatin InterMediate C-4 rosuvastatin interMediates C-4 rosuvastatin intermediates C-4 ROSUVASTATIN CALCIUM INTERMEDIATE C-1 2-Methyl-2-propanyl 6-O-acetyl-2,4-dideoxy-3,5-O-isopropylidene-D -erythro-hexonate (4R-Cis)-6-[(Acetyloxy)methyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid,1,1-Dimethyethyl Ester (4R-CIS)-6-[(ACETYLOXY)METHYL]-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID,1,1-DIMETHYLETHYL ESTER (4R-Cis)-6-[(Acetyloxy) methyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid,1,1-Dimethyethyl Ester (4R-Cis)-6-[(Acetyloxy) methyl]-2,2-Dimethyl-1,3-Dioxane-4-Acetic Acid,1,1-Diemthyethyl Ester (4R-CIS)-6-[(ACETYLOXY METHYL)]-2,2-DIMETHYL-1,3-DIOXANE-4-ACETIC ACID,1,1-DIMETHYETHYL ESTER (4R-cis)-6-[ (acetyloxy)methyl ]-2,2-dimethyl-1,3-dioxane-4-acetic acid,1,1-dimethylethyl ester
CAS	1540426-95-6
EINECS	1806241-263-5

1540426-95-6 - Physico-chemical Properties

Molecular Formula	C13H20N2O4
Molar Mass	268.31
Density	1.20±0.1 g/cm3(Predicted)
Boling Point	508.0±40.0 °C(Predicted)
Flash Point	150.334 °C
pKa	2.59±0.10(Predicted)
Storage Condition	RT, closed, dry
Use	Intermediate

1540426-95-6 - Introduction

rosuvastatin intermediates C- 4, often abbreviated as EDGMA.

Nature:
1. Appearance: is a colorless to light yellow liquid.
2. Molecular formula: C12H18O6.
3. Molecular weight: 258.27g/mol.
4. Melting point:-15 ° C.
5. Boiling Point: 149 ° C.
6. Density: 1.12 g/mL.
7. Solubility: Soluble in water and organic solvents.

Use:
EDGMA is an important chemical with a variety of uses in the chemical industry, including:
1. As a polymer monomer: EDGMA can be used to synthesize resins and polymers, such as vinyl alcohol copolymers, polyamides, polyesters, etc.
2. As a paint material: EDGMA can be used to prepare high-gloss coatings with excellent wear resistance and chemical resistance.
3. As a gel material: EDGMA can be used for the preparation of gel materials, in cosmetics, drug controlled release and other fields have a wide range of applications.

Method:
The preparation method of EDGMA can be carried out through the following steps:
1. Reaction of 2,2-dimethyl -1,3-dioxolane (DMDO) with acetic anhydride yields 6-acetoxy-2, 2-dimethyl-1, 3-dioxopentanoic acid (DMAE).
2. In the presence of DMAE, DMAE is reacted with ethanol to form EDGMA.

Safety Information:
EDGMA is a chemical, the use of the need to pay attention to the following safety matters:
1. Avoid contact with skin and eyes, such as contact should immediately rinse with plenty of water.
2. Avoid inhaling gas or solution, and operate in a well-ventilated place when using it.
3. Do not drink or swallow EDGMA.
4. Store away from fire and oxidant, and keep sealed.
5. Protective gloves, goggles and protective clothing should be worn during use.

When using EDGMA, you should strictly follow the relevant safety regulations, follow the correct operating steps, and comply with the relevant local regulations.

Last Update：2024-04-09 19:05:46