1547-29-1
3-FLUORO-2-HYDROXYPYRIDINE
CAS: 1547-29-1
Molecular Formula: C5H4FNO
1547-29-1 - Names and Identifiers
| Name | 3-FLUORO-2-HYDROXYPYRIDINE |
| Synonyms | 3-fluoropyridin-2-o 3-Fluoro-2-pyridinol 3-Fluoropyridin-2-ol 3-fluoropyridin-2(1H)-one 3-FLUORO-2-HYDROXYPYRIDINE 3-Fluoro-2-hydroxypyridine, 3-fluoro-2-pyridone 4,4,4-trifluoro-3-hydroxy-3-(trifluoromethyl)butanoic acid |
| CAS | 1547-29-1 |
| InChI | InChI=1/C5H4FNO/c6-4-2-1-3-7-5(4)8/h1-3H,(H,7,8) |
1547-29-1 - Physico-chemical Properties
| Molecular Formula | C5H4FNO |
| Molar Mass | 113.09 |
| Density | 1.26±0.1 g/cm3(Predicted) |
| Melting Point | 157-161℃ |
| Boling Point | 273.1±40.0 °C(Predicted) |
| Flash Point | 119°C |
| Vapor Presure | 0.00585mmHg at 25°C |
| Appearance | White powder |
| pKa | 10.96±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.508 |
| MDL | MFCD03095042 |
1547-29-1 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Class | IRRITANT |
1547-29-1 - Introduction
3-FLUORO-2-HYDROXYPYRIDINE(3-fluoro-2-hydroxypyridine) is an organic compound with the molecular formula C5H4FNO, with one fluorine atom and one hydroxyl group substituted at the 2 and 3 positions of pyridine. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
-Appearance: 3-FLUORO-2-HYDROXYPYRIDINE is a colorless or light yellow crystal or liquid.
-Solubility: It is soluble in water and common organic solvents, such as ethanol and dimethyl ether.
-Melting point and boiling point: Its melting point is about 38-39 degrees Celsius, and the boiling point is about 190 degrees Celsius (the corresponding pressure is 760 mmHg).
-Chemical properties: It is an acidic compound that can be acidified.
Use:
- 3-FLUORO-2-HYDROXYPYRIDINE is commonly used as an intermediate in organic synthesis. It can be used as a raw material for drug synthesis and pesticide synthesis.
-It can also be used to prepare fluorine-containing organic compounds, such as natural products and functional compounds containing fluorine.
Method:
The preparation of-3-FLUORO-2-HYDROXYPYRIDINE can be obtained by reacting pyridine and hydrogen fluoride in ammonia or a specific organic solvent. Reaction conditions generally require heating and the use of a catalyst.
Safety Information:
-Since 3-FLUORO-2-HYDROXYPYRIDINE is a chemical, pay attention to safe operation when using it, and operate in accordance with relevant regulations and operating procedures.
- 3-FLUORO-2-HYDROXYPYRIDINE may cause irritation and pain when in contact with the skin, eyes or by inhalation. Contact with skin and eyes should be avoided, and protective glasses and gloves should be worn when using.
-During storage and transportation, it should be sealed and placed in a dry, ventilated and dark place.
Nature:
-Appearance: 3-FLUORO-2-HYDROXYPYRIDINE is a colorless or light yellow crystal or liquid.
-Solubility: It is soluble in water and common organic solvents, such as ethanol and dimethyl ether.
-Melting point and boiling point: Its melting point is about 38-39 degrees Celsius, and the boiling point is about 190 degrees Celsius (the corresponding pressure is 760 mmHg).
-Chemical properties: It is an acidic compound that can be acidified.
Use:
- 3-FLUORO-2-HYDROXYPYRIDINE is commonly used as an intermediate in organic synthesis. It can be used as a raw material for drug synthesis and pesticide synthesis.
-It can also be used to prepare fluorine-containing organic compounds, such as natural products and functional compounds containing fluorine.
Method:
The preparation of-3-FLUORO-2-HYDROXYPYRIDINE can be obtained by reacting pyridine and hydrogen fluoride in ammonia or a specific organic solvent. Reaction conditions generally require heating and the use of a catalyst.
Safety Information:
-Since 3-FLUORO-2-HYDROXYPYRIDINE is a chemical, pay attention to safe operation when using it, and operate in accordance with relevant regulations and operating procedures.
- 3-FLUORO-2-HYDROXYPYRIDINE may cause irritation and pain when in contact with the skin, eyes or by inhalation. Contact with skin and eyes should be avoided, and protective glasses and gloves should be worn when using.
-During storage and transportation, it should be sealed and placed in a dry, ventilated and dark place.
Last Update：2024-04-09 21:04:16
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