154934-99-3

154934-99-3 - Names and Identifiers

Name	2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE
Synonyms	BUTTPARK 3718-31 2-fluoro-1,3-dimethoxy-4-nitrobenzene 2-Chloro-4-(trifluoromethyl)pyrimidine-5-carbonyl 2-chloro-4-(trifluoromethyl)-5-pyrimidinecarbonyl chloride 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE 5-Pyrimidinecarbonyl chloride, 2-chloro-4-(trifluoromethyl)-
CAS	154934-99-3
InChI	InChI=1/C8H8FNO4/c1-13-6-4-3-5(10(11)12)8(14-2)7(6)9/h3-4H,1-2H3

154934-99-3 - Physico-chemical Properties

Molecular Formula	C6HCl2F3N2O
Molar Mass	244.99
Density	1.658±0.06 g/cm3(Predicted)
Melting Point	158 °C
Boling Point	54°C 0,15mm
Flash Point	148.287°C
Vapor Presure	0.001mmHg at 25°C
pKa	-6.23±0.29(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.513

154934-99-3 - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3265
HS Code	29335990
Hazard Class	CORROSIVE

154934-99-3 - Introduction

2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE is a chemical compound with the chemical formula C8H3Cl2F3NO and a molecular weight of 257.02g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 2-chroo-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE is a colorless to slightly yellow crystal or liquid.
-Melting point: The melting point range is -1 ° C to 3 ° C.
-Boiling point: Its boiling point is 59 ° C (specified value).
-Density: Its density is 1.61g/cm³ (specified value).
-Solubility: 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE is soluble in organic solvents (such as ether, carbon tetrachloride, etc.), but insoluble in water.

Use:
-2-choro-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE is commonly used as a reagent for certain organic synthesis reactions, such as fluorination reactions, esterification reactions, etc.
-It is also used in catalysis and catalyst intermediates in organic synthesis.

Method:
2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE is generally prepared by combining 2-CHLORO-4-(TRIFLUOROMETHYL) pyridine-5-hydroxy with an acylating reagent (such as thionyl CHLORIDE) the reaction is obtained under suitable conditions.

Safety Information:
- 2-CHLORO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBONYL CHLORIDE is a corrosive substance and care should be taken to avoid contact with skin, eyes and respiratory tract.
-Wear protective gloves, glasses and respiratory protection when used.
-storage should be sealed, away from the fire and oxidant.
-If you come into contact with this compound, rinse the affected area immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15