155905-77-4
Boc-L-Cyclobutylglycine
CAS: 155905-77-4
Molecular Formula: C11H19NO4
155905-77-4 - Names and Identifiers
155905-77-4 - Physico-chemical Properties
| Molecular Formula | C11H19NO4 |
| Molar Mass | 229.27 |
| Density | 1.169±0.06 g/cm3(Predicted) |
| Boling Point | 379.1±25.0 °C(Predicted) |
| pKa | 4.06±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
155905-77-4 - Introduction
Boc-L-Cyclobutylglycine is an amino acid protecting group whose properties can be described in the following ways:
Nature:
Boc-L-Cyclobutylglycine is a white crystalline solid that is stable at room temperature. It has a relatively large molecular weight and good solubility. It is a chiral molecule and has only the L-configuration.
Use:
Boc-L-Cyclobutylglycine is widely used in organic synthesis. As an amino acid protecting group, it can protect the amino group in the amino acid to prevent undesired reaction. Furthermore, Boc-L-Cyclobutylglycine can also be used as starting materials for peptide synthesis or as synthetic intermediates.
Method:
The preparation of Boc-L-Cyclobutylglycine is generally carried out by the following steps: First, L-cyclobutylglycine is reacted with a Boc protecting agent (tert-butoxycarbonyl chloride) to form Boc-L-Cyclobutylglycine. The reaction is usually carried out under basic conditions, such as using sodium carbonate or triethylamine as a base catalyst.
Safety Information:
The Boc-L-Cyclobutylglycine is relatively stable under normal operating conditions, but it is still necessary to pay attention to safe operation. During the operation, it should avoid contact with skin and eyes. Wear appropriate personal protective equipment, such as lab gloves and safety glasses. In addition, it should be operated in a well-ventilated laboratory to avoid or reduce its inhalation or ingestion. If an accident occurs, immediately flush the contaminated area with plenty of water and seek medical help. When storing and handling, it should be stored in a dry, cool, well-ventilated place, away from heat and flammable materials.
Nature:
Boc-L-Cyclobutylglycine is a white crystalline solid that is stable at room temperature. It has a relatively large molecular weight and good solubility. It is a chiral molecule and has only the L-configuration.
Use:
Boc-L-Cyclobutylglycine is widely used in organic synthesis. As an amino acid protecting group, it can protect the amino group in the amino acid to prevent undesired reaction. Furthermore, Boc-L-Cyclobutylglycine can also be used as starting materials for peptide synthesis or as synthetic intermediates.
Method:
The preparation of Boc-L-Cyclobutylglycine is generally carried out by the following steps: First, L-cyclobutylglycine is reacted with a Boc protecting agent (tert-butoxycarbonyl chloride) to form Boc-L-Cyclobutylglycine. The reaction is usually carried out under basic conditions, such as using sodium carbonate or triethylamine as a base catalyst.
Safety Information:
The Boc-L-Cyclobutylglycine is relatively stable under normal operating conditions, but it is still necessary to pay attention to safe operation. During the operation, it should avoid contact with skin and eyes. Wear appropriate personal protective equipment, such as lab gloves and safety glasses. In addition, it should be operated in a well-ventilated laboratory to avoid or reduce its inhalation or ingestion. If an accident occurs, immediately flush the contaminated area with plenty of water and seek medical help. When storing and handling, it should be stored in a dry, cool, well-ventilated place, away from heat and flammable materials.
Last Update：2024-04-09 21:01:54
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