159724-40-0
3-(4-Morpholinyl)aniline
CAS: 159724-40-0
Molecular Formula: C10H14N2O
159724-40-0 - Names and Identifiers
| Name | 3-(4-Morpholinyl)aniline |
| Synonyms | AKOS BB-8950 3-MORPHOLIN-4-YLANILINE 3-morpholinobenzenamine 3-(4-Morpholinyl)aniline 4-(3-Aminophenyl)morpholine 3-Morpholin-4-yl-phenylamine |
| CAS | 159724-40-0 |
| InChI | InChI=1/C10H14N2O/c11-9-2-1-3-10(8-9)12-4-6-13-7-5-12/h1-3,8H,4-7,11H2 |
159724-40-0 - Physico-chemical Properties
| Molecular Formula | C10H14N2O |
| Molar Mass | 178.23 |
| Density | 1.149±0.06 g/cm3(Predicted) |
| Melting Point | 118 °C |
| Boling Point | 0°C |
| Flash Point | 0°C |
| Solubility | Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated) |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Solid |
| Color | Pale Brown to Brown |
| pKa | 5.27±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.59 |
159724-40-0 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| Hazard Note | Harmful |
| Hazard Class | IRRITANT |
159724-40-0 - Introduction
3-(4-Morpholinyl)aniline, chemical formula C13H15N, is an organic compound. It has the following properties:
1. Appearance: 3-(4-Morpholinyl)aniline is a colorless to light yellow crystal or crystalline powder.
2. Solubility: It is soluble in alcohol, chloroform, benzene and dimethylformamide and other organic solvents, insoluble in water.
3. Melting Point: its melting point is 82-84 degrees Celsius.
The main uses of 3-(4-Morpholinyl)aniline are:
1. Dye intermediates: 3-(4-Morpholinyl)aniline is an important intermediate for the synthesis of certain organic dyes, which is widely used in textile, leather and plastic industries.
2. Pharmaceutical: It is also used as an important intermediate in the synthesis of some drugs.
Preparation of 3-(4-Morpholinyl)aniline:
can be obtained by reacting aniline with 4-morpholinol. The specific preparation process is as follows:
First, under appropriate conditions, aniline is reacted with 4-Morpholinyl alcohol to generate 3-(4-Morpholinyl)aniline. The reaction can be carried out in a suitable solvent and at a relatively low temperature.
Safety Information:
3-(4-Morpholinyl)aniline is relatively safe under normal conditions of use and storage. However, as a chemical substance, it may cause irritation and damage to the human body, so pay attention to the following aspects:
1. Avoid direct contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water.
2. Use should wear appropriate protective equipment, such as gloves and protective glasses.
3. Use in a well-ventilated place to avoid inhaling its vapor or dust.
4. After use, the container should be sealed and stored in a dry, cool and ventilated place.
1. Appearance: 3-(4-Morpholinyl)aniline is a colorless to light yellow crystal or crystalline powder.
2. Solubility: It is soluble in alcohol, chloroform, benzene and dimethylformamide and other organic solvents, insoluble in water.
3. Melting Point: its melting point is 82-84 degrees Celsius.
The main uses of 3-(4-Morpholinyl)aniline are:
1. Dye intermediates: 3-(4-Morpholinyl)aniline is an important intermediate for the synthesis of certain organic dyes, which is widely used in textile, leather and plastic industries.
2. Pharmaceutical: It is also used as an important intermediate in the synthesis of some drugs.
Preparation of 3-(4-Morpholinyl)aniline:
can be obtained by reacting aniline with 4-morpholinol. The specific preparation process is as follows:
First, under appropriate conditions, aniline is reacted with 4-Morpholinyl alcohol to generate 3-(4-Morpholinyl)aniline. The reaction can be carried out in a suitable solvent and at a relatively low temperature.
Safety Information:
3-(4-Morpholinyl)aniline is relatively safe under normal conditions of use and storage. However, as a chemical substance, it may cause irritation and damage to the human body, so pay attention to the following aspects:
1. Avoid direct contact with skin and eyes, such as accidental contact, should immediately rinse with plenty of water.
2. Use should wear appropriate protective equipment, such as gloves and protective glasses.
3. Use in a well-ventilated place to avoid inhaling its vapor or dust.
4. After use, the container should be sealed and stored in a dry, cool and ventilated place.
Last Update：2024-04-09 21:01:54
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