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159899-65-7

Adrenomedullin (22-52) (Human)

CAS: 159899-65-7

Molecular Formula: C159H252N46O48

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159899-65-7 - Names and Identifiers

Name Adrenomedullin (22-52) (Human)
Synonyms ADRENOMEDULLIN (HUMAN, 22-52)
ADRENOMEDULLIN (22-52) (HUMAN)
Adrenomedullin (22-52) (Human)
TVQKLAHQIYQFTDKDKDNVAPRSKISPQGY-NH2
ADRENOMEDULLIN FRAGMENT 22-52 HUMAN
THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2
H-THR-VAL-GLN-LYS-LEU-ALA-HIS-GLN-ILE-TYR-GLN-PHE-THR-ASP-LYS-ASP-LYS-ASP-ASN-VAL-ALA-PRO-ARG-SER-LYS-ILE-SER-PRO-GLN-GLY-TYR-NH2
CAS 159899-65-7

159899-65-7 - Physico-chemical Properties

Molecular FormulaC159H252N46O48
Molar Mass3575.98
Storage Condition-20°C
In vitro study Adrenomedullin (AM) (22-52), human shows no effect on hindlimb perfusion pressure responses to adrenomedullin (ADM) at 120 nmol. However, Adrenomedullin (AM) (22-52), human selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) at 30 nmol, with similar effect to that of CGRP antagonist. Adrenomedullin (AM) (22-52), human competitively inhibits the binding of the Adrenomedullin in a dose-dependent manner, inhibits Adrenomedullin -induced cAMP accumulation in rat vascular smooth muscle cells.

159899-65-7 - Risk and Safety

WGK Germany3

159899-65-7 - Reference Information

biological activity Adrenomedullin (AM) (22-52), human,NH2 end truncated adrenomedullin analog, is adrenomedullin (adrenomedullin receptor) receptor antagonist, and is also in the vascular bed of the hind limb of the cat, it also has an antagonistic effect on calcitonin gene-related peptide (CGRP) receptors.
target Adrenomedullin receptor, CGRP receptor
in vitro research Adrenomedullin (AM) (22-52), human shows no effect on hindlimb perfusion pressure responses to adrenomedullin (ADM) at 120 nmol. However, Adrenomedullin (AM) (22-52), human selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) at 30 nmol, with similar effect to that of CGRP antagonist. Adrenomedullin (AM) (22-52), human competitively inhibits the binding of the Adrenomedullin in a dose-dependent manner, inhibits Adrenomedullin -induced cAMP accumulation in rat vascular smooth muscle cells.
Last Update:2024-04-09 01:59:59
159899-65-7
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Tel: 400-968-2212
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Mobile: 18916960931
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Shanghai Macklin Biochemical Co., Ltd
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CAS: 159899-65-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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Product Name: Adrenomedullin (AM) (22-52), human Visit Supplier Webpage Request for quotation
CAS: 159899-65-7
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
MedChemExpress (MCE)
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CAS: 159899-65-7
Tel: 609-228-6898
Email: sales@medchemexpress.com
     tech@medchemexpress.com
Mobile: 609-228-6898
Shanghai Yuanye Bio-Technology Co., Ltd.
Product Name: Adrenomedullin (22-52) (Human) Visit Supplier Webpage Request for quotation
CAS: 159899-65-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
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