16176-74-2
1H-Indole-4-acetic acid
CAS: 16176-74-2
Molecular Formula: C10H9NO2
16176-74-2 - Names and Identifiers
16176-74-2 - Physico-chemical Properties
| Molecular Formula | C10H9NO2 |
| Molar Mass | 175.18 |
| Density | 1.354±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 207-208℃ (ethanol benzene ) |
| Boling Point | 415.0±20.0 °C(Predicted) |
| pKa | 4.43±0.30(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
16176-74-2 - Introduction
1H-Indole-4-acetic acid, also known as indoleacetic acid, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Indole acetic acid is a white crystalline solid.
-Solubility: It is slightly soluble in water, and more easily soluble in organic solvents such as ethanol and chloroform.
-Chemical properties: Indole acetic acid can react through the carboxylic acid functional group, for example, it can form the corresponding amide compound with amine.
Use:
-Biochemistry: Indole acetic acid is an important compound widely used in biochemical research. It can be used as a component of media lacking tryptophan and purine and can promote plant growth.
-Drugs: Indole acetic acid has anti-inflammatory effects, so it can be used in drug development and manufacturing.
Method:
The preparation of indole acetic acid can be carried out by the reaction of indole and bromoacetic acid. First, bromoacetic acid is reacted with a base (e. G., sodium carbonate) to give 2-bromoacetic acid, which is then treated with hydrochloric acid to give 2-bromoacetic acid. Finally, the 2-bromoacetic acid obtained by the reaction is reacted with indole under suitable reaction conditions to form indole acetic acid.
Safety Information:
-Indole acetic acid is an organic compound. Regular laboratory safety procedures should be followed during use to avoid contact with skin and eyes.
-Avoid inhalation of IAA dust or vapors and use with appropriate personal protective equipment such as gloves, goggles and protective clothing.
-Waste disposal should be carried out in accordance with local environmental regulations to avoid pollution to the environment.
Nature:
-Appearance: Indole acetic acid is a white crystalline solid.
-Solubility: It is slightly soluble in water, and more easily soluble in organic solvents such as ethanol and chloroform.
-Chemical properties: Indole acetic acid can react through the carboxylic acid functional group, for example, it can form the corresponding amide compound with amine.
Use:
-Biochemistry: Indole acetic acid is an important compound widely used in biochemical research. It can be used as a component of media lacking tryptophan and purine and can promote plant growth.
-Drugs: Indole acetic acid has anti-inflammatory effects, so it can be used in drug development and manufacturing.
Method:
The preparation of indole acetic acid can be carried out by the reaction of indole and bromoacetic acid. First, bromoacetic acid is reacted with a base (e. G., sodium carbonate) to give 2-bromoacetic acid, which is then treated with hydrochloric acid to give 2-bromoacetic acid. Finally, the 2-bromoacetic acid obtained by the reaction is reacted with indole under suitable reaction conditions to form indole acetic acid.
Safety Information:
-Indole acetic acid is an organic compound. Regular laboratory safety procedures should be followed during use to avoid contact with skin and eyes.
-Avoid inhalation of IAA dust or vapors and use with appropriate personal protective equipment such as gloves, goggles and protective clothing.
-Waste disposal should be carried out in accordance with local environmental regulations to avoid pollution to the environment.
Last Update：2024-04-09 21:01:54
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