| Molecular Formula | C27H36N2O5 |
| Molar Mass | 468.59 |
| Density | 1.129±0.06 g/cm3(Predicted) |
| Boling Point | 623.5±55.0 °C(Predicted) |
| Appearance | powder |
| Color | white to beige |
| pKa | 9.07±0.10(Predicted) |
| Storage Condition | 2-8°C |
| UN IDs | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.134 ml | 10.67 ml | 21.341 ml |
| 5 mM | 0.427 ml | 2.134 ml | 4.268 ml |
| 10 mM | 0.213 ml | 1.067 ml | 2.134 ml |
| 5 mM | 0.043 ml | 0.213 ml | 0.427 ml |
| biological activity | I-CBP112 is an effective selective CBP/p300 inhibitor, and the dissociation constants Kd values for CBP and p300 are 151±6 nM and 167±8 nM respectively. |
| target | TargetValue cBP (cell-free say) 151 nm (kd) p300 (cell-free say) 167 nm (kd) |
| Target | Value |
| CBP (Cell-free assay) | 151 nM(Kd) |
| p300 (Cell-free assay) | 167 nM(Kd) |