The Properties, Uses, preparation and safety information of HDBTU, also known as Dipyrido[3,2-d:2 ',3'-f][1,3,2]-diazaphospholene-4,6-dion are as follows:
Nature:
HDBTU is a white to light yellow solid. It has relatively high thermal stability and flammability. This compound is soluble in solvents, but has a low solubility in water.
Use:
HDBTU is commonly used as a phosphorylating reagent in organic synthesis reactions. It can be used for the synthesis of organic phosphate and organic phosphoric acid amide compounds, can also be used for the synthesis of phosphorus containing polymer materials.
Method:
HDBTU can be obtained by reacting the corresponding 4-amino derivative with hexafluorophosphoric acid. Specifically, 3,4-dihydro-4-oxo -1,2, 3-benzotriazol-3-amine can be first synthesized and then reacted with trimethylthiourea to obtain the target product.
Safety Information:
Because HDBTU is flammable, care should be taken to avoid causing fire or explosion when handling this compound. In addition, it may also cause irritation to the skin, eyes and respiratory system, so it is necessary to wear appropriate protective equipment during operation and ensure that the operation is carried out in a well-ventilated place. It is recommended that when using or storing this compound, maintain appropriate precautions and handle it in accordance with relevant regulations.