169280-83-5
TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE
CAS: 169280-83-5
Molecular Formula: C11H16N2O3
169280-83-5 - Names and Identifiers
169280-83-5 - Physico-chemical Properties
| Molecular Formula | C11H16N2O3 |
| Molar Mass | 224.26 |
| Density | 1.209 |
| Boling Point | 332.8±32.0 °C(Predicted) |
| Flash Point | 155.1°C |
| Vapor Presure | 5.67E-05mmHg at 25°C |
| pKa | 12.35±0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.567 |
| MDL | MFCD07186264 |
169280-83-5 - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. |
| HS Code | 29309090 |
169280-83-5 - Introduction
TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE is an organic compound with the following properties:
1. Appearance and physical properties: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE is commonly a colorless or white solid with a molecular formula of C, a molecular weight of 200.25. It is a derivative of pyridine methanol, which contains a Boc-protecting group (Boc represents tert-butylaminocarbonyl) in the molecular structure, so it has a certain stability.
2. Chemical properties: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE is soluble in common organic solvents such as dimethylformamide (DMF) and dichloromethane (DCM). It can remove the amino protecting group Boc under basic conditions, thereby generating a free amino site.
3. Application: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE is a commonly used intermediate in organic synthesis, mainly used to prepare compounds with specific biological activities. In the study of medicinal chemistry and biological activity, it can be used to synthesize anti-tumor, anti-inflammatory, antibiotics and other drug molecules. In addition, it can also be used for catalyst synthesis and catalyst support for organic synthesis reactions.
4. Preparation method: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE can be obtained by reacting pyridine methanol with tert-butamol. First, at a lower temperature, pyridine methanol and tert-butyl alcohol react to generate Boc protecting group derivatives, and then the Boc protecting group is removed by hydrolysis to obtain the target product.
5. Safety information: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE should be operated safely during use and storage, avoid contact with skin and inhalation, and wear protective gloves, protective glasses and protective masks. At the same time, contact with strong oxidants and strong acids should be avoided during storage. In case of swallowing or accidental contact, medical attention should be sought immediately.
1. Appearance and physical properties: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE is commonly a colorless or white solid with a molecular formula of C, a molecular weight of 200.25. It is a derivative of pyridine methanol, which contains a Boc-protecting group (Boc represents tert-butylaminocarbonyl) in the molecular structure, so it has a certain stability.
2. Chemical properties: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE is soluble in common organic solvents such as dimethylformamide (DMF) and dichloromethane (DCM). It can remove the amino protecting group Boc under basic conditions, thereby generating a free amino site.
3. Application: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE is a commonly used intermediate in organic synthesis, mainly used to prepare compounds with specific biological activities. In the study of medicinal chemistry and biological activity, it can be used to synthesize anti-tumor, anti-inflammatory, antibiotics and other drug molecules. In addition, it can also be used for catalyst synthesis and catalyst support for organic synthesis reactions.
4. Preparation method: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE can be obtained by reacting pyridine methanol with tert-butamol. First, at a lower temperature, pyridine methanol and tert-butyl alcohol react to generate Boc protecting group derivatives, and then the Boc protecting group is removed by hydrolysis to obtain the target product.
5. Safety information: TERT-BUTYL [5-(HYDROXYMETHYL)PYRIDIN-2-YL)CARBAMATE should be operated safely during use and storage, avoid contact with skin and inhalation, and wear protective gloves, protective glasses and protective masks. At the same time, contact with strong oxidants and strong acids should be avoided during storage. In case of swallowing or accidental contact, medical attention should be sought immediately.
Last Update：2024-04-09 21:11:58
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Product Name: tert-Butyl (5-(hydroxymethyl)pyridin-2-yl)carbamate Request for quotationCAS: 169280-83-5
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Mobile: 18916960931
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Product Name: Tert-butyl 5-(hydroxymethyl)pyridin-2-ylcarbamate Visit Supplier Webpage Request for quotationCAS: 169280-83-5
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Product Name: 2-(Boc-Amino)-5-Pyridinemethanol Visit Supplier Webpage Request for quotationCAS: 169280-83-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
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Product Name: 2-(Boc-Amino)-5-Pyridinemethanol Visit Supplier Webpage Request for quotation
CAS: 169280-83-5
Tel: 18301782025
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CAS: 169280-83-5
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