170366-90-2
Ethanone, 2,2,2-trifluoro-1-(1H-indol-5-yl)- (9CI)
CAS: 170366-90-2
Molecular Formula: C10H6F3NO
170366-90-2 - Names and Identifiers
170366-90-2 - Physico-chemical Properties
| Molecular Formula | C10H6F3NO |
| Molar Mass | 213.16 |
| Density | 1.423±0.06 g/cm3(Predicted) |
| Boling Point | 308.6±37.0 °C(Predicted) |
| pKa | 15.45±0.30(Predicted) |
| Storage Condition | 2-8°C |
170366-90-2 - Introduction
Ethanone, 2,2,2-trifluoro-1-(1H-indol-5-yl)- (9CI), also known as TFAA(trifluoroacetyl indole), is an organic compound. The following is a description of some of its properties, uses, methods and safety information:
Nature:
-Appearance: TFAA is a colorless to pale yellow solid.
-Solubility: TFAA is easily soluble in organic solvents (such as methanol, chloroform, dimethylformamide), but has low solubility in water.
-Melting point: The melting point of TFAA is about 82-85°C.
Use:
-Organic synthesis: TFAA is widely used as an acylating agent in organic synthesis, and can be used to introduce trifluoroacetyl (trifluoroacetyl) into compounds, thereby changing their properties or increasing their stability.
-Pharmaceutical research: TFAA is also used in pharmaceutical research as a labeling reagent or intermediate.
Method:
- TFAA has many preparation methods, one of which is obtained by the reaction of 1H-indole -5-methanol with trifluoroacetic acid chloride (trifluoroacetyl chloride). This reaction process requires the appropriate catalyst and reaction conditions.
Safety Information:
- TFAA is an irritating compound that may cause irritation or burning after contact with the skin or eyes. When using or handling TFAA, appropriate protective measures should be taken, such as wearing chemical gloves, safety glasses and protective clothing.
- TFAA is also combustible. It should be kept away from fire and high temperature, stored in a well-ventilated place, and avoid contact with oxidants and other substances.
Please note that this information is for reference only. Before using TFAA, please carefully read and follow the relevant safety operation procedures and regulatory requirements.
Nature:
-Appearance: TFAA is a colorless to pale yellow solid.
-Solubility: TFAA is easily soluble in organic solvents (such as methanol, chloroform, dimethylformamide), but has low solubility in water.
-Melting point: The melting point of TFAA is about 82-85°C.
Use:
-Organic synthesis: TFAA is widely used as an acylating agent in organic synthesis, and can be used to introduce trifluoroacetyl (trifluoroacetyl) into compounds, thereby changing their properties or increasing their stability.
-Pharmaceutical research: TFAA is also used in pharmaceutical research as a labeling reagent or intermediate.
Method:
- TFAA has many preparation methods, one of which is obtained by the reaction of 1H-indole -5-methanol with trifluoroacetic acid chloride (trifluoroacetyl chloride). This reaction process requires the appropriate catalyst and reaction conditions.
Safety Information:
- TFAA is an irritating compound that may cause irritation or burning after contact with the skin or eyes. When using or handling TFAA, appropriate protective measures should be taken, such as wearing chemical gloves, safety glasses and protective clothing.
- TFAA is also combustible. It should be kept away from fire and high temperature, stored in a well-ventilated place, and avoid contact with oxidants and other substances.
Please note that this information is for reference only. Before using TFAA, please carefully read and follow the relevant safety operation procedures and regulatory requirements.
Last Update：2024-04-09 15:17:53
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Product Name: 2,2,2-Trifluoro-1-(1H-indol-5-yl)ethanone Request for quotationCAS: 170366-90-2
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Product Name: Ethanone, 2,2,2-trifluoro-1-(1H-indol-5-yl)- (9CI) Visit Supplier Webpage Request for quotation
CAS: 170366-90-2
Tel: 18301782025
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CAS: 170366-90-2
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Email: 3008007409@qq.com
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