171860-41-6
(2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one
CAS: 171860-41-6
Molecular Formula: C18H17NO4
171860-41-6 - Names and Identifiers
| Name | (2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one |
| Synonyms | (2S, 4S) Z-5-OXAZOLIDINONE(2-PH, 4-ME) (2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin (2S,4S)-Benzyl 4-methyl-5-oxo-2-phenyloxazolidine-3-carboxylate benzyl (2S,4S)-4-methyl-5-oxo-2-phenyloxazolidine-3-carboxylate (2S,4S)-3-BENZYLOXYCARBONYL-4-METHYL-2-PHENYL-1,3-OXAZOLIDIN-5-ONE (2S,4S)-3-Benzyloxycarbonyl-4-methyl-2-phenyl-1,3-oxazolidin-5-one Benzyl (2S,4S)-4-methyl-5-oxo-2-phenyl-1,3-oxazolidine-3-carboxylate 3-Oxazolidinecarboxylic acid, 4-methyl-5-oxo-2-phenyl-, phenylmethyl ester, (2S,4S)- |
| CAS | 171860-41-6 |
| InChI | InChI=1/C18H17NO4/c1-13-17(20)23-16(15-10-6-3-7-11-15)19(13)18(21)22-12-14-8-4-2-5-9-14/h2-11,13,16H,12H2,1H3/t13-,16-/m0/s1 |
171860-41-6 - Physico-chemical Properties
| Molecular Formula | C18H17NO4 |
| Molar Mass | 311.33 |
| Density | 1.246 |
| Boling Point | 509.982°C at 760 mmHg |
| Flash Point | 262.228°C |
| Vapor Presure | 0mmHg at 25°C |
| Refractive Index | 1.585 |
171860-41-6 - Introduction
2S,4S)-3-oxazolidin-5-one is a compound. The following is an introduction to its properties, uses, preparation methods and safety information:
Nature:
The molecular formula of the compound is C17H15NO3, and its appearance is a white crystalline solid. It has a melting point of 76-78°C, a boiling point of 450.2±55.0°C and a molecular weight of 289.31g/mol.
Use:
(2S,4S)-3-oxazolidin-5-one can be used as a pharmaceutical intermediate. The compound has a wide range of applications in the field of synthetic chemistry, especially for the synthesis of bioactive molecules containing 1,3-oxazoline -5-One structures.
Method:
(2S,4S)-the preparation method of 3-oxazolidin-5-one usually includes:
1. The reaction of 2-benzyloxycarbonyl-2-methyl-1-styrenyl alcohol with copper methyl sulfate under cyanide gas yields 2-methyl -1, 3-oxazoline-5-dione.
2. 2-Methyl-l, 3-oxazoline-5-dione is reacted with an Enantioselective Catalyst under appropriate conditions to obtain (2S,4S)-phenanthrene, 3-oxazolidin-5-one.
Safety Information:
When handling and using (2S,4S)-, 3-oxazolidin-5-one, you need to pay attention to safety precautions. The compound may be toxic to humans, so wear appropriate protective gloves and goggles, and ensure that you operate in a well-ventilated area. In case of contact with skin or eyes, rinse immediately with plenty of water. If swallowed, consult a doctor immediately and give appropriate treatment. Please read the safety data form of the product carefully before use and follow all safety procedures.
Nature:
The molecular formula of the compound is C17H15NO3, and its appearance is a white crystalline solid. It has a melting point of 76-78°C, a boiling point of 450.2±55.0°C and a molecular weight of 289.31g/mol.
Use:
(2S,4S)-3-oxazolidin-5-one can be used as a pharmaceutical intermediate. The compound has a wide range of applications in the field of synthetic chemistry, especially for the synthesis of bioactive molecules containing 1,3-oxazoline -5-One structures.
Method:
(2S,4S)-the preparation method of 3-oxazolidin-5-one usually includes:
1. The reaction of 2-benzyloxycarbonyl-2-methyl-1-styrenyl alcohol with copper methyl sulfate under cyanide gas yields 2-methyl -1, 3-oxazoline-5-dione.
2. 2-Methyl-l, 3-oxazoline-5-dione is reacted with an Enantioselective Catalyst under appropriate conditions to obtain (2S,4S)-phenanthrene, 3-oxazolidin-5-one.
Safety Information:
When handling and using (2S,4S)-, 3-oxazolidin-5-one, you need to pay attention to safety precautions. The compound may be toxic to humans, so wear appropriate protective gloves and goggles, and ensure that you operate in a well-ventilated area. In case of contact with skin or eyes, rinse immediately with plenty of water. If swallowed, consult a doctor immediately and give appropriate treatment. Please read the safety data form of the product carefully before use and follow all safety procedures.
Last Update：2024-04-09 20:49:11
Supplier List
View History