173676-59-0

Name	4-Chloro-2(1,1-Dihydroxy-2,2,2-Trifluoroethyl)Aniline HCL (SD570)
Synonyms	E2 E-2 Efavirenz Intermediate E-2 4-Chloro-2-(Trifluoroacetyl)Aniline HCl 4-Chloro-2-trifluoro acetyl aniline HCL 4-Chloro-2-trifluoroacetylanilineHCl(E2) 4-Chloro-2-(Trifluoro Acetyl)Aniline Hcl 4-chloro-2-(trifluoroacetyl)anilinium chloride 4-Chloro-2-trifluoro acetylaniline hydrochloride 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride 4-Chloro-2-(trifluoroacetyl) aniline hydrochloride 4-CHLORO-2,2,2-TRIFLUORO ACETYL ANILINE HYDROCHLORIDE 4-Chloro-2-trifluoroacetylanilinehydrochloridehydrate 4-Chloro-2-Trifluoroacetylaniline Hydrochloride Hydrate 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride hydrate 4-CHLORO-2(1,1-DIHYDROXY-2,2,2-TRIFLUOROETHYL)ANILINE HCL 4-Chloro-2-(Trifluoroacetyl)aniline Hydrochloride Hydrate (E-2) 1-(2-aMino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrochloride 4-Chloro-2(1,1-Dihydroxy-2,2,2-Trifluoroethyl)Aniline HCL (SD570) 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethan-1-one hydrochloride 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoro-ethanone Hydrochloride Hydrate 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethan-1-one hydrate hydrochloride
CAS	173676-59-0
EINECS	605-687-6
InChI	InChI=1/C8H5ClF3NO.ClH/c9-4-1-2-6(13)5(3-4)7(14)8(10,11)12;/h1-3H,13H2;1H

Molecular Formula	C8H5ClF3NO.ClH.H2O
Molar Mass	278.06
Melting Point	156-158°C
Boling Point	282.3°C at 760 mmHg
Flash Point	124.5°C
Vapor Presure	0.00339mmHg at 25°C
Storage Condition	Inert atmosphere,Room Temperature
Physical and Chemical Properties	Appearance: light yellow powder

Hazard Symbols

Xi - Irritant

overview	efavirenz (Elavirenz), the chemical name is (4S) -6-chlorine -4-(cyclopropylacetylene)-4-(trifluoromethyl)-benzo -1,4-dihydrooxazole -2-one, developed by Merck Company of the United States, is a specific drug against HIV, it belongs to the category of non-nuclear reverse transcriptase inhibitors and is mainly used for human immune virus A (HIV type 1). It was approved for listing by the Food and Drug Administration (FDA) in February 1999 with a Sustiva trade name.
properties	favirenz belongs to the category of non-nucleoside reverse transcriptase inhibitor (NNRTI-non-nucleoside reverse transcriptase inhibitor) Anti-retroviral (antiretrovirals) drugs, both nucleoside-based RTI and non-nucleoside-based RTI are intended to inhibit the same target, namely reverse transcriptase (reverse transcriptase enzyme). This enzyme is transcribed from RNA into DNA, and it is extremely important for virus reproduction.
adverse reactions	side effects are often accompanied by the following psychopathological symptoms: insomnia, confusion, confusion, memory loss, emotional depression, etc. Rash, nausea, dizziness and headache may also occur. According to Weilun may cause defects in newborn babies, so it should not be used for women with pregnancy opportunities, the safety of use in infants has not yet been confirmed; the use of Eviron may also lead to a false positive urine test for marijuana substances.

Last Update：2024-04-09 20:52:54

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