175277-44-8
5-(Trifluoromethyl)pyridine-2-carboxamide oxime
CAS: 175277-44-8
Molecular Formula: C7H6F3N3O
175277-44-8 - Names and Identifiers
175277-44-8 - Physico-chemical Properties
| Molecular Formula | C7H6F3N3O |
| Molar Mass | 205.14 |
| Density | 1.527g/cm3 |
| Melting Point | 124-126°C |
| Boling Point | 328.112°C at 760 mmHg |
| Flash Point | 152.237°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.527 |
175277-44-8 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S22 - Do not breathe dust. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Class | IRRITANT |
175277-44-8 - Introduction
5-(Trifluoromethyl)pyridine-2-carboxamide oxime, chemical formula C7H4F3N3O, molecular weight of 191.12g/mol. It is a solid powder, colorless or light yellow, with a pungent odor.
The compound has certain toxicity and corrosiveness, so personal protective measures should be paid attention to during use. Avoid direct contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with clean water and seek medical assistance.
5-(Trifluoromethyl)pyridine-2-carboxamide oxime is mainly used as catalysts and intermediates in organic synthesis. It is often used in chemical processes for the reduction of aromatic aldehydes and ketones or the reduction of halogenated acidification products. In addition, it can also be used as a protecting group removing agent in organic synthesis for removing the p-hydroxyl protecting group.
The preparation method of the compound can be obtained by reacting 5-aminopyridine with trifluoroformaldehyde. The 5-aminopyridine is first dissolved in a suitable solvent and then the trifluoroformaldehyde solution is slowly added dropwise. At the end of the reaction, the product is isolated by crystallization or other isolation methods.
Finally, it should be emphasized that for the use of any chemical, the operating procedures and safety operation manuals must be strictly followed to ensure the safety and effectiveness of use. When chemicals are used in laboratory or industrial environments, adequate risk assessments should be conducted in advance and appropriate safety measures should be taken, such as wearing chemical protective gloves, goggles and protective clothing.
The compound has certain toxicity and corrosiveness, so personal protective measures should be paid attention to during use. Avoid direct contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with clean water and seek medical assistance.
5-(Trifluoromethyl)pyridine-2-carboxamide oxime is mainly used as catalysts and intermediates in organic synthesis. It is often used in chemical processes for the reduction of aromatic aldehydes and ketones or the reduction of halogenated acidification products. In addition, it can also be used as a protecting group removing agent in organic synthesis for removing the p-hydroxyl protecting group.
The preparation method of the compound can be obtained by reacting 5-aminopyridine with trifluoroformaldehyde. The 5-aminopyridine is first dissolved in a suitable solvent and then the trifluoroformaldehyde solution is slowly added dropwise. At the end of the reaction, the product is isolated by crystallization or other isolation methods.
Finally, it should be emphasized that for the use of any chemical, the operating procedures and safety operation manuals must be strictly followed to ensure the safety and effectiveness of use. When chemicals are used in laboratory or industrial environments, adequate risk assessments should be conducted in advance and appropriate safety measures should be taken, such as wearing chemical protective gloves, goggles and protective clothing.
Last Update：2024-04-10 22:29:15
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Product Name: (E)-N'-hydroxy-5-(trifluoromethyl)pyridine-2-carboximidamide Visit Supplier Webpage Request for quotationCAS: 175277-44-8
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Product Name: 5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME Visit Supplier Webpage Request for quotation
CAS: 175277-44-8
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CAS: 175277-44-8
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