175291-56-2
Fmoc-O-(Benzylphospho)-L-Threonine
CAS: 175291-56-2
Molecular Formula: C26H26NO8P
175291-56-2 - Names and Identifiers
| Name | Fmoc-O-(Benzylphospho)-L-Threonine |
| Synonyms | FMOC-THR(HPO3BZL)-OH Fmoc-Thr(HPO3Bzl)-OH Fmoc-Thr(PO(OBzl))-OH FMOC-L-THR(PO(OBZL)OH) FMOC-THR(PO(OBZL)OH)-OH FMOC-L-THR(PO(OBZL)OH)-OH FMOC-THREONINE(PO(OBZL)OH)-OH FMOC-O-BENZYL-L-PHOSPHOTHREONINE Fmoc-O-(Benzylphospho)-L-Threonine N-ALPHA-FMOC-O-BENZYL-L-PHOSPHOTHREONINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-BENZYLOXY-PHOSPHONO-L-THREONINE O-[(benzyloxy)(hydroxy)phosphoryl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-threonine |
| CAS | 175291-56-2 |
| InChI | InChI=1/C26H26NO8P/c1-17(35-36(31,32)34-15-18-9-3-2-4-10-18)24(25(28)29)27-26(30)33-16-23-21-13-7-5-11-19(21)20-12-6-8-14-22(20)23/h2-14,17,23-24H,15-16H2,1H3,(H,27,30)(H,28,29)(H,31,32)/t17-,24+/m0/s1 |
| InChIKey | HOFDVXHILSPFNS-OSPHWJPCSA-N |
175291-56-2 - Physico-chemical Properties
| Molecular Formula | C26H26NO8P |
| Molar Mass | 511.46 |
| Density | 1.377±0.06 g/cm3(Predicted) |
| Melting Point | 155.6°C |
| Appearance | Solid |
| pKa | 1.42±0.50(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.614 |
| MDL | MFCD00797870 |
175291-56-2 - Risk and Safety
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
175291-56-2 - Introduction
Fmoc-O-(benzylphosphate)-L-Threonine is a compound that has the following properties:
1. Appearance: Fmoc-O-(benzylphosphate)-L-Threonine is a white to off-white solid.
2. Solubility: It can be dissolved in some organic solvents, such as dimethylformamide (DMF), dichloromethane, etc.
Fmoc-O-(benzylphosphate)-L-Threonine has some important applications in chemical research and biomedicine:
1. Protein synthesis: Fmoc-O-(benzylphosphate)-L-Threonine Fmoc synthesis strategy commonly used in solid phase synthesis (SPPS) for protein and peptide synthesis.
2. Pharmaceutical research: It can be used for drug synthesis and preparation of drug delivery systems in drug research.
Fmoc-O-(benzylphosphate)-L-Threonine can be synthesized:
react Fmoc-threonine with benzyl alcohol and active acid (for example: DCC) to generate Fmoc-threonine dibenzyl phosphate, and then through acid catalysis and deprotection reaction, the final Fmoc-O-(benzylphosphate)-L-Threonine is obtained.
Regarding safety information, Fmoc-O-(benzylphosphate)-L-Threonine is a chemical substance that needs to be operated under suitable laboratory conditions. When operating, it is necessary to wear appropriate personal protective equipment, such as laboratory gloves and goggles. It may be irritating to the skin, eyes and respiratory system and should be avoided from exposure above the skin. When handling this substance, it is important to closely follow safe practices and comply with relevant regulations and guidelines. During use, this compound should be stored and handled correctly to ensure safety and stability.
1. Appearance: Fmoc-O-(benzylphosphate)-L-Threonine is a white to off-white solid.
2. Solubility: It can be dissolved in some organic solvents, such as dimethylformamide (DMF), dichloromethane, etc.
Fmoc-O-(benzylphosphate)-L-Threonine has some important applications in chemical research and biomedicine:
1. Protein synthesis: Fmoc-O-(benzylphosphate)-L-Threonine Fmoc synthesis strategy commonly used in solid phase synthesis (SPPS) for protein and peptide synthesis.
2. Pharmaceutical research: It can be used for drug synthesis and preparation of drug delivery systems in drug research.
Fmoc-O-(benzylphosphate)-L-Threonine can be synthesized:
react Fmoc-threonine with benzyl alcohol and active acid (for example: DCC) to generate Fmoc-threonine dibenzyl phosphate, and then through acid catalysis and deprotection reaction, the final Fmoc-O-(benzylphosphate)-L-Threonine is obtained.
Regarding safety information, Fmoc-O-(benzylphosphate)-L-Threonine is a chemical substance that needs to be operated under suitable laboratory conditions. When operating, it is necessary to wear appropriate personal protective equipment, such as laboratory gloves and goggles. It may be irritating to the skin, eyes and respiratory system and should be avoided from exposure above the skin. When handling this substance, it is important to closely follow safe practices and comply with relevant regulations and guidelines. During use, this compound should be stored and handled correctly to ensure safety and stability.
Last Update：2024-04-09 20:02:46
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