1823-63-8
2,2,2-trifluoro-1-(4-hydroxyphenyl)ethanone
CAS: 1823-63-8
Molecular Formula: C8H5F3O2
1823-63-8 - Names and Identifiers
1823-63-8 - Physico-chemical Properties
| Molecular Formula | C8H5F3O2 |
| Molar Mass | 190.12 |
| Density | 1.400±0.06 g/cm3(Predicted) |
| Melting Point | 114 °C |
| Boling Point | 261.9±35.0 °C(Predicted) |
| Flash Point | 112.2°C |
| Vapor Presure | 0.007mmHg at 25°C |
| pKa | 7.60±0.13(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.481 |
1823-63-8 - Introduction
2,2,2-trifluoro-1-(4-hydroxyphenyl)ethanone, also known as TFHA, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: TFHA is a colorless liquid or light yellow oily substance.
-Solubility: It dissolves in many organic solvents, such as ethanol, ether and chloroform.
-Melting point: The melting point of TFHA is 25-27 degrees Celsius.
-Boiling point: Its boiling point is 185-190 degrees Celsius.
Use:
-Chemical synthesis: TFHA can be used as a reagent or catalyst in organic synthesis, and is widely used in the fields of dyes, drugs, medicine and pesticides.
-Reaction medium: Due to its unique properties, TFHA can be used as a non-polar medium and as a solvent and catalyst in some specific organic reactions.
-Flame retardant: The fluorine atom and benzene ring structure of TFHA give it excellent flame retardant properties, so it can also be used as one of the components of flame retardant.
Method:
The preparation method of TFHA includes:
-First prepare substituted benzoic acid:
1. 4-hydroxybenzoic acid and glacial acetic acid are heated to react to generate p-Hydroxybenzoic acid.
2. Add sodium bicarbonate to neutralize the reaction solution.
-Reprepare 2,2,2-trifluoro-1-(4-hydroxyphenyl)ethanone:
Trifluoroacetic anhydride was added to the reaction solution of p-Hydroxybenzoic acid, followed by stirring, and an increase in the temperature of the reaction solution was observed. After completion of the reaction, TFHA was obtained by distillation extraction. The preparation process requires control of parameters such as temperature and reaction time.
Safety Information:
- TFHA is an organofluorine compound that can cause irritation and burns to the skin, eyes and respiratory tract.
-Wear protective gloves, safety glasses and respiratory protection when using.
-Avoid contact with oxidants, strong acids and alkalis.
Nature:
-Appearance: TFHA is a colorless liquid or light yellow oily substance.
-Solubility: It dissolves in many organic solvents, such as ethanol, ether and chloroform.
-Melting point: The melting point of TFHA is 25-27 degrees Celsius.
-Boiling point: Its boiling point is 185-190 degrees Celsius.
Use:
-Chemical synthesis: TFHA can be used as a reagent or catalyst in organic synthesis, and is widely used in the fields of dyes, drugs, medicine and pesticides.
-Reaction medium: Due to its unique properties, TFHA can be used as a non-polar medium and as a solvent and catalyst in some specific organic reactions.
-Flame retardant: The fluorine atom and benzene ring structure of TFHA give it excellent flame retardant properties, so it can also be used as one of the components of flame retardant.
Method:
The preparation method of TFHA includes:
-First prepare substituted benzoic acid:
1. 4-hydroxybenzoic acid and glacial acetic acid are heated to react to generate p-Hydroxybenzoic acid.
2. Add sodium bicarbonate to neutralize the reaction solution.
-Reprepare 2,2,2-trifluoro-1-(4-hydroxyphenyl)ethanone:
Trifluoroacetic anhydride was added to the reaction solution of p-Hydroxybenzoic acid, followed by stirring, and an increase in the temperature of the reaction solution was observed. After completion of the reaction, TFHA was obtained by distillation extraction. The preparation process requires control of parameters such as temperature and reaction time.
Safety Information:
- TFHA is an organofluorine compound that can cause irritation and burns to the skin, eyes and respiratory tract.
-Wear protective gloves, safety glasses and respiratory protection when using.
-Avoid contact with oxidants, strong acids and alkalis.
Last Update：2024-04-09 21:04:16
Supplier List
Featured ProductsSpot supply
Product Name: 2,2,2-Trifluoro-4’-hydroxyacetophenone Visit Supplier Webpage Request for quotationCAS: 1823-63-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 2,2,2-Trifluoro-4'-hydroxyacetophenone Request for quotationCAS: 1823-63-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2,2,2-Trifluoro-4’-hydroxyacetophenone Visit Supplier Webpage Request for quotationCAS: 1823-63-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 2,2,2-TRIFLUORO-1-(4-HYDROXY-PHENYL)-ETHANONE Visit Supplier Webpage Request for quotation
CAS: 1823-63-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1823-63-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: 2,2,2-Trifluoro-4’-hydroxyacetophenone Visit Supplier Webpage Request for quotationCAS: 1823-63-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 2,2,2-Trifluoro-4'-hydroxyacetophenone Request for quotationCAS: 1823-63-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 2,2,2-Trifluoro-4’-hydroxyacetophenone Visit Supplier Webpage Request for quotationCAS: 1823-63-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 2,2,2-TRIFLUORO-1-(4-HYDROXY-PHENYL)-ETHANONE Visit Supplier Webpage Request for quotation
CAS: 1823-63-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 1823-63-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History