18372-22-0
Methyl indolyl-3-glyoxylate
CAS: 18372-22-0
Molecular Formula: C11H9NO3
18372-22-0 - Names and Identifiers
18372-22-0 - Physico-chemical Properties
| Molecular Formula | C11H9NO3 |
| Molar Mass | 203.19 |
| Density | 1.324±0.06 g/cm3(Predicted) |
| Melting Point | 227-230 °C (lit.) |
| Boling Point | 383.2±15.0 °C(Predicted) |
| Flash Point | 185.6°C |
| Solubility | Acetone, Methanol |
| Vapor Presure | 4.46E-06mmHg at 25°C |
| Appearance | Pale yellow fine powder |
| Color | Pale Yellow Fine |
| pKa | 14.54±0.30(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Stability | Temperature Sensitive |
| Refractive Index | 1.635 |
| MDL | MFCD00047173 |
| Physical and Chemical Properties | WGK Germany:3 |
18372-22-0 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
18372-22-0 - Introduction
Methyl indolyl-3-glyoxylate is an organic compound with the chemical formula C11H9NO2. The following is its nature, use, preparation and safety information:
Nature:
Methyl indolyl-3-glyoxylate is a colorless to light yellow liquid. It has aroma, soluble in alcohol and ether solvents, insoluble in water. Contact with oxygen and strong oxidants should be avoided during storage and use.
Use:
Methyl indolyl-3-glyoxylate is often used as an intermediate in organic synthesis in chemical laboratories and can be used to synthesize indole derivatives. In addition, it is also used in pharmaceutical research, Pesticide Synthesis and the preparation of fragrances and flavors.
Method:
The preparation method of Methyl indolyl-3-glyoxylate can be obtained by reacting indole -3-ethanol with acetic anhydride. First, indole -3-ethanol is reacted with acetic anhydride in an anhydrous environment to produce indole -3-glycolic acid acetate. Then, this compound is subjected to an esterification reaction under an acidic condition to obtain a Methyl indolyl-3-glyoxylate.
Safety Information:
Methyl indolyl-3-glyoxylate is irritating and may cause irritation to the eyes, skin and respiratory system. It is necessary to maintain good ventilation and wear appropriate personal protective equipment, such as protective glasses, protective gloves and protective masks. Keep away from flammable and explosive materials during storage and operation. In case of contact or inhalation, rinse immediately with water and seek medical assistance.
Nature:
Methyl indolyl-3-glyoxylate is a colorless to light yellow liquid. It has aroma, soluble in alcohol and ether solvents, insoluble in water. Contact with oxygen and strong oxidants should be avoided during storage and use.
Use:
Methyl indolyl-3-glyoxylate is often used as an intermediate in organic synthesis in chemical laboratories and can be used to synthesize indole derivatives. In addition, it is also used in pharmaceutical research, Pesticide Synthesis and the preparation of fragrances and flavors.
Method:
The preparation method of Methyl indolyl-3-glyoxylate can be obtained by reacting indole -3-ethanol with acetic anhydride. First, indole -3-ethanol is reacted with acetic anhydride in an anhydrous environment to produce indole -3-glycolic acid acetate. Then, this compound is subjected to an esterification reaction under an acidic condition to obtain a Methyl indolyl-3-glyoxylate.
Safety Information:
Methyl indolyl-3-glyoxylate is irritating and may cause irritation to the eyes, skin and respiratory system. It is necessary to maintain good ventilation and wear appropriate personal protective equipment, such as protective glasses, protective gloves and protective masks. Keep away from flammable and explosive materials during storage and operation. In case of contact or inhalation, rinse immediately with water and seek medical assistance.
Last Update：2024-04-09 21:01:54
Supplier List
Featured ProductsSpot supply
Product Name: Methyl 2-(1H-indol-3-yl)-2-oxoacetate Visit Supplier Webpage Request for quotationCAS: 18372-22-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Methyl 2-(1H-indol-3-yl)-2-oxoacetate Request for quotationCAS: 18372-22-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Methyl 3-indoleglyoxylate Visit Supplier Webpage Request for quotationCAS: 18372-22-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Methyl Indol-3-Glyoxylate Visit Supplier Webpage Request for quotationCAS: 18372-22-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: Methyl 2-(1H-indol-3-yl)-2-oxoacetate Visit Supplier Webpage Request for quotationCAS: 18372-22-0
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Methyl 2-(1H-indol-3-yl)-2-oxoacetate Request for quotationCAS: 18372-22-0
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Methyl 3-indoleglyoxylate Visit Supplier Webpage Request for quotationCAS: 18372-22-0
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Methyl Indol-3-Glyoxylate Visit Supplier Webpage Request for quotationCAS: 18372-22-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History