183741-86-8
5-(TERT-BUTOXYCARBONYLAMINO)-2-METHOXYPYRIDINE-4-CARBOXYLIC ACID
CAS: 183741-86-8
Molecular Formula: C12H16N2O5
183741-86-8 - Names and Identifiers
| Name | 5-(TERT-BUTOXYCARBONYLAMINO)-2-METHOXYPYRIDINE-4-CARBOXYLIC ACID |
| Synonyms | 5-(Boc-aMino)-2-Methoxyisonicotinic Acid 5-(Boc-aMino)-2-Methoxypyridine-4-carboxylic acid 5-(tert-Butoxycarbonyl)-2-methoxyisonicotinic acid 5-(N-Boc-amino)-2-methoxypyridine-4-carboxylic acid 5-((tert-Butoxycarbonyl)aMino)-2-Methoxyisonicotinic acid 5-(tert-butoxycarbonylaMio)-2-Methoxypyridine-4-carboxylic acid 5-(TERT-BUTOXYCARBONYLAMINO)-2-METHOXYPYRIDINE-4-CARBOXYLIC ACID 5-(tert-Butoxycarbonylamino)-2-methoxypyridine-4-carboxylic acid |
| CAS | 183741-86-8 |
| EINECS | 214-589-6 |
| InChI | InChI=1/C12H16N2O5/c1-12(2,3)19-11(17)14-8-6-13-9(18-4)5-7(8)10(15)16/h5-6H,1-4H3,(H,14,17)(H,15,16) |
183741-86-8 - Physico-chemical Properties
| Molecular Formula | C12H16N2O5 |
| Molar Mass | 268.27 |
| Density | 1.288g/cm3 |
| Boling Point | 415°C at 760 mmHg |
| Flash Point | 204.8°C |
| Vapor Presure | 1.24E-07mmHg at 25°C |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.565 |
183741-86-8 - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| HS Code | 29333990 |
183741-86-8 - Introduction
5-(TERT-BUTOXYCARBONYLAMINO)-ACID, also known as BOC-protected acid, is an organic compound. Its chemical formula is C14H19N2O5.
Nature:
1. Appearance: white solid
2. Melting Point: about 80-85 ° C
3. Solubility: Soluble in some organic solvents such as methanol, ethanol and dimethylformamide
Use:
5-(TERT-BUTOXYCARBONYLAMINO)-ACID is often used as a protecting group in organic synthesis. It can react with an amino acid or amine to form a protected amino acid or amine derivative to protect its active group. The compounds can be used as agents for the temporary protection of amino acids in synthetic polypeptides or pharmaceutical research.
Method:
5-(TERT-BUTOXYCARBONYLAMINO)-ACID can be synthesized by the following steps:
1. 2-methoxypyridine-4-carboxylic acid reacts with dimethylformamide to generate 2-methoxypyridine-4-carboxamide.
2. Under the catalysis of a base, 2-methoxypyridine-4-carboxamide reacts with tert-butoxycarbonyl isocyanate to generate 5-(TERT-BUTOXYCARBONYLAMINO)-5-acid.
Safety Information:
1. 5-(TERT-BUTOXYCARBONYLAMINO)-The ACID is irritating and should avoid contact with skin and eyes.
2. During operation, attention should be paid to isolation and appropriate protective measures, including wearing protective glasses and gloves.
3. Should be stored in a dry, ventilated and away from the fire, avoid contact with the oxidant.
Nature:
1. Appearance: white solid
2. Melting Point: about 80-85 ° C
3. Solubility: Soluble in some organic solvents such as methanol, ethanol and dimethylformamide
Use:
5-(TERT-BUTOXYCARBONYLAMINO)-ACID is often used as a protecting group in organic synthesis. It can react with an amino acid or amine to form a protected amino acid or amine derivative to protect its active group. The compounds can be used as agents for the temporary protection of amino acids in synthetic polypeptides or pharmaceutical research.
Method:
5-(TERT-BUTOXYCARBONYLAMINO)-ACID can be synthesized by the following steps:
1. 2-methoxypyridine-4-carboxylic acid reacts with dimethylformamide to generate 2-methoxypyridine-4-carboxamide.
2. Under the catalysis of a base, 2-methoxypyridine-4-carboxamide reacts with tert-butoxycarbonyl isocyanate to generate 5-(TERT-BUTOXYCARBONYLAMINO)-5-acid.
Safety Information:
1. 5-(TERT-BUTOXYCARBONYLAMINO)-The ACID is irritating and should avoid contact with skin and eyes.
2. During operation, attention should be paid to isolation and appropriate protective measures, including wearing protective glasses and gloves.
3. Should be stored in a dry, ventilated and away from the fire, avoid contact with the oxidant.
Last Update：2024-04-09 02:00:43
Supplier List
Featured ProductsSpot supply
Product Name: 5-(Boc-amino)-2-methoxyisonicotinic Acid Visit Supplier Webpage Request for quotationCAS: 183741-86-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Multiple SpecificationsSpot supply
Product Name: 5-(Boc-amino)-2-methoxyisonicotinic Acid Request for quotationCAS: 183741-86-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 5-(Boc-amino)-2-methoxyisonicotinic Acid Visit Supplier Webpage Request for quotationCAS: 183741-86-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 5-(TERT-BUTOXYCARBONYLAMINO)-2-METHOXYPYRIDINE-4-CARBOXYLIC ACID Visit Supplier Webpage Request for quotation
CAS: 183741-86-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 183741-86-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: 5-(Boc-amino)-2-methoxyisonicotinic Acid Visit Supplier Webpage Request for quotationCAS: 183741-86-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Multiple SpecificationsSpot supply
Product Name: 5-(Boc-amino)-2-methoxyisonicotinic Acid Request for quotationCAS: 183741-86-8
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: 5-(Boc-amino)-2-methoxyisonicotinic Acid Visit Supplier Webpage Request for quotationCAS: 183741-86-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: 5-(TERT-BUTOXYCARBONYLAMINO)-2-METHOXYPYRIDINE-4-CARBOXYLIC ACID Visit Supplier Webpage Request for quotation
CAS: 183741-86-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 183741-86-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History