185985-40-4
2,3-dichloro-5-fluoropyridine
CAS: 185985-40-4
Molecular Formula: C5H2Cl2FN
185985-40-4 - Names and Identifiers
| Name | 2,3-dichloro-5-fluoropyridine |
| Synonyms | 2,3-dichloro-5-fluoropyridine 2,3-Dichloro-5-fluoropyridine Pyridine, 2,3-dichloro-5-fluoro- pyridine, 2,3-dichloro-5-fluoro- |
| CAS | 185985-40-4 |
| EINECS | 251-156-6 |
| InChI | InChI=1/C5H2Cl2FN/c6-4-1-3(8)2-9-5(4)7/h1-2H |
185985-40-4 - Physico-chemical Properties
| Molecular Formula | C5H2Cl2FN |
| Molar Mass | 165.98 |
| Density | 1.498±0.06 g/cm3(Predicted) |
| Boling Point | 174.0±35.0 °C(Predicted) |
| Flash Point | 59.1°C |
| Water Solubility | Slightly soluble in chloroform, methanol and water. |
| Vapor Presure | 1.65mmHg at 25°C |
| Appearance | Solid |
| pKa | -2.97±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.528 |
185985-40-4 - Introduction
2,3-dichloro-5-fluoropyridine, also known as 2,3-dichloro-5-fluoropyridine, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-chemical formula: C5H2Cl2FN
-Molecular weight: 153.98g/mol
-Appearance: Colorless to light yellow crystal or liquid
-Melting point:-2 ° C
-Boiling point: 80-82 ° C
-Solubility: Soluble in organic solvents, insoluble in water
Use:
2,3-dichloro-5-fluoropyridine has certain application value in organic synthesis and pharmaceutical chemistry, and is usually used as an intermediate or raw material.
Method:
The preparation of 2,3-dichloro-5-fluoropyridine can usually be carried out by the following steps:
1. 2,3-dibromo-5-fluoropyridine is reacted with anhydrous ammonium chloride to obtain the intermediate of 2,3-dichloro-5-fluoropyridine.
2. In the presence of alkali, and then react with sodium bisulfite to obtain the target product.
Safety Information:
- 2,3-dichloro-5-fluoropyridine requires attention to protective measures during use, including wearing protective gloves, goggles and masks.
-Avoid breathing its vapors or contact with skin, eyes and clothing.
-Maintain good ventilation during operation.
-If taken by mistake or inhaled, seek medical assistance immediately.
-Detailed safety operation procedures should be formulated and followed according to specific conditions and relevant safety regulations.
Please note that 2,3-dichloro-5-fluoropyridine is a chemical and must follow safe operating procedures and consult a professional for guidance.
Nature:
-chemical formula: C5H2Cl2FN
-Molecular weight: 153.98g/mol
-Appearance: Colorless to light yellow crystal or liquid
-Melting point:-2 ° C
-Boiling point: 80-82 ° C
-Solubility: Soluble in organic solvents, insoluble in water
Use:
2,3-dichloro-5-fluoropyridine has certain application value in organic synthesis and pharmaceutical chemistry, and is usually used as an intermediate or raw material.
Method:
The preparation of 2,3-dichloro-5-fluoropyridine can usually be carried out by the following steps:
1. 2,3-dibromo-5-fluoropyridine is reacted with anhydrous ammonium chloride to obtain the intermediate of 2,3-dichloro-5-fluoropyridine.
2. In the presence of alkali, and then react with sodium bisulfite to obtain the target product.
Safety Information:
- 2,3-dichloro-5-fluoropyridine requires attention to protective measures during use, including wearing protective gloves, goggles and masks.
-Avoid breathing its vapors or contact with skin, eyes and clothing.
-Maintain good ventilation during operation.
-If taken by mistake or inhaled, seek medical assistance immediately.
-Detailed safety operation procedures should be formulated and followed according to specific conditions and relevant safety regulations.
Please note that 2,3-dichloro-5-fluoropyridine is a chemical and must follow safe operating procedures and consult a professional for guidance.
Last Update：2024-04-09 19:05:47
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