18881-17-9

18881-17-9 - Names and Identifiers

Name	(S)-1,2,3,4-Tetrahydroisoquinoline-3-Methanol
Synonyms	(S)-1,2,3,4-Tetrahydroisoquinolylmethan-3-Ol (S)-1,2,3,4-Tetrahydroisoquinoline-3-Methanol (S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-METHANOL (3S)-1,2,3,4-Tetrahydro-3-isoquinolinemethanol (S)-1,2,3,4-Tetrahydro-3-isoquinolinylmethanol 3-HYDROXYMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE 3-Hydroxymethyl-1,2,3,4-Tetrahydroisoquinoline (S)-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL-METHANOL (S)-1,2,3,4-Tetrahydroisoquinolin-3-Yl-Methanol (3S)-1,2,3,4-Tetrahydroisoquinolin-3-Ylmethanol (S)-(-)-1,2,3,4-Tetrahydro-3-Isoquinolinemethanol (S)-(-)-1,2,3,4-Tetrahydroisoquinoline-3-Methanol (S)-3-Hydroxymethyl-1,2,3,4-Tetrahydroisoquinoline (S)-3-HYDROXYMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE (S)-3-(Hydroxymethyl)-1,2,3,4-Tetrahydroisoquinoline (3S)-3-(Hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline (3S)-3-(Hydroxymethyl)-1,2,3,4-Tetrahydroisoquinolinium
CAS	18881-17-9 1881-17-0
InChI	InChI=1/C10H13NO/c12-7-10-5-8-3-1-2-4-9(8)6-11-10/h1-4,10-12H,5-7H2/p+1/t10-/m0/s1

18881-17-9 - Physico-chemical Properties

Molecular Formula	C10H13NO
Molar Mass	163.22
Density	1.0508 (rough estimate)
Melting Point	114-116°C(lit.)
Boling Point	290.31°C (rough estimate)
Flash Point	147°C
Vapor Presure	0.000305mmHg at 25°C
Appearance	White powder
Color	Off-white
pKa	14.57±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	-97 ° (C=0.2, MeOH)
MDL	MFCD01631316
Physical and Chemical Properties	WGK Germany:3

18881-17-9 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3
HS Code	29339900
Hazard Note	Irritant

18881-17-9 - Introduction

(S)-1,2,3, (S), also known as (S)-(-)-Tetrahydroisoquinoline, is an organic compound.

Nature:
(S)-1,2,3, is a colorless to light yellow liquid with a special fragrance. Its chemical formula is C10H13NO and its molecular weight is 163.22g/mol. It is an optically active compound with an optical rotation of -8.2(c = 10, ethanol). In addition, it is soluble in water, alcohol and ether.

Use:
(S)-1,2,3, commonly used in medicine and organic synthesis. As a chiral intermediate, it is widely used in the synthesis of chiral compounds with pharmacological activity. It can also be used in the preparation of dyes, pesticides and other organic compounds.

Method:
(S)-1,2,3, can be synthesized by a variety of methods. The commonly used method is the use of asymmetric catalytic reaction in organic synthesis, through the appropriate chiral catalyst catalytic asymmetric hydrogenation reaction preparation. Other preparation methods may also involve chemical reduction or hydrogenation reactions.

Safety Information:
(S)-1,2,3, belongs to organic compounds, has certain toxicity, so pay attention to safety during operation. It is irritating and corrosive and may cause irritation to the eyes, skin and respiratory tract. During operation, wear appropriate protective measures such as safety glasses, gloves and respiratory protection equipment. At the same time, contact with fire sources should be avoided, and care should be taken to avoid high temperature and direct sunlight during storage. When using or handling this compound, it is best to operate in a well-ventilated area to avoid inhaling gas or swallowing. If contact with skin or eyes is made, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 21:32:38