19056-79-2

19056-79-2 - Names and Identifiers

Name	2-((4-Chlorophenylamino)methylene)malonic acid diethyl ester
Synonyms	DIETHYL 2-[(4-CHLOROANILINO)METHYLENE]MALONATE diethyl 2-((4-chlorophenylaMino)Methylene)Malonate 2-((4-Chlorophenylamino)methylene)malonic acid diethyl ester 2-((4-CHLOROPHENYLAMINO)METHYLENE)MALONIC ACID DIETHYL ESTER Propanedioic acid, 2-[[(4-chlorophenyl)amino]methylene]-, 1,3-diethyl ester
CAS	19056-79-2
InChI	InChI=1/C14H16ClNO4/c1-3-19-13(17)12(14(18)20-4-2)9-16-11-7-5-10(15)6-8-11/h5-9,16H,3-4H2,1-2H3

19056-79-2 - Physico-chemical Properties

Molecular Formula	C14H16ClNO4
Molar Mass	297.73
Density	1.257±0.06 g/cm3(Predicted)
Melting Point	45-46 °C
Boling Point	360.2±42.0 °C(Predicted)
Flash Point	171.7°C
Vapor Presure	2.25E-05mmHg at 25°C
pKa	-1.42±0.70(Predicted)
Storage Condition	2-8℃
Refractive Index	1.56
Use	This product is for scientific research only and shall not be used for other purposes.

19056-79-2 - Introduction

2-((4-Chlorophenylamino)methyl) malonic acid diethyl ester, also known as CMEAA. The following is an introduction to the nature, use, formulation and safety information of CMEAA:

Nature:
-Appearance: Colorless to light yellow oily liquid.
-Solubility: Soluble in organic solvents, such as ethanol, ether, dichloromethane, etc.
-Melting point: About -17 ℃.
-Boiling point: About 365 ℃.
-Density: about 1.167g/cm³.

Use:
CMEAA has a wide range of applications in the chemical field, including but not limited to the following:
-Drug research: It can be used as a drug intermediate for the synthesis of specific types of drugs.
-Surfactant: can be used as a lubricant and emulsifier.
-Catalyst: It can be used as a carrier for catalysts in organic chemical reactions.

Method:
The preparation of CMEAA usually includes the following steps:
1. Diethyl malate and chloroaniline were added to the reaction vessel.
2. The reaction is carried out at an appropriate temperature, and ammonium sulfate or other acidic catalysts are used to promote the reaction.
3. After the reaction, the target product is obtained by distillation and other purification methods.

Safety Information:
- CMEAA has a certain degree of irritation and should avoid contact with skin and eyes.
-During use or storage, keep away from fire and high temperature.
-Wear appropriate protective gloves and glasses when using.
-If inhaled accidentally or ingested by mistake, please seek medical attention promptly.

Last Update：2024-04-09 02:00:44