19750-02-8
3-Amino-1H-pyrazole-4-carboxylic acid ethyl ester
CAS: 19750-02-8;1260243-04-6
Molecular Formula: C6H9N3O2
19750-02-8 - Names and Identifiers
19750-02-8 - Physico-chemical Properties
| Molecular Formula | C6H9N3O2 |
| Molar Mass | 155.15 |
| Density | 1.318g/cm3 |
| Boling Point | 349.2°C at 760 mmHg |
| Flash Point | 165°C |
| Vapor Presure | 4.79E-05mmHg at 25°C |
| Storage Condition | 2-8 ℃, dark |
| Sensitive | Irritant |
| Refractive Index | 1.584 |
| MDL | MFCD00114562 |
19750-02-8 - Introduction
acid ethyl ester, chemical formula C7H8N2O2, is an organic compound. The following is a description of the relevant Properties, Uses, methods and safety information:
Nature:
-acid ethyl ester is a white crystal with a special smell.
-It is soluble in a variety of organic solvents at room temperature, such as ethanol, ether, chloroform, etc.
-The melting point of this compound is about 121-123°C.
-It is more stable under acidic conditions, but will degrade under alkaline conditions.
Use:
-or acid ethyl ester is commonly used as an amine group protecting reagent in organic synthesis.
-It can be combined by acid or nucleophile to form a temporary protecting group, Protect the amine group from reacting with other reagents, and increase the selectivity of organic synthesis.
-In addition, it can also be used to synthesize 3-aminopyrazole acyl compounds required for various studies.
Method:
-The preparation of acid ethyl ester is usually obtained by reacting 3-aminopyrazole with ethyl formate under alkaline conditions.
-Reaction Ethyl formate is added to the solution of 3-aminopyrazole, and a base is added to promote the reaction.
-After the reaction is completed, the target product is obtained through steps such as acidification and crystallization.
Safety Information:
-acid ethyl ester is irritating and corrosive.
-After contact with skin and eyes, rinse immediately with plenty of water and seek medical help.
-Good ventilation measures should be taken during operation to avoid inhalation and contact.
-Store away from high temperature, fire and oxidant.
-Please follow the chemical safety procedures for use.
Nature:
-acid ethyl ester is a white crystal with a special smell.
-It is soluble in a variety of organic solvents at room temperature, such as ethanol, ether, chloroform, etc.
-The melting point of this compound is about 121-123°C.
-It is more stable under acidic conditions, but will degrade under alkaline conditions.
Use:
-or acid ethyl ester is commonly used as an amine group protecting reagent in organic synthesis.
-It can be combined by acid or nucleophile to form a temporary protecting group, Protect the amine group from reacting with other reagents, and increase the selectivity of organic synthesis.
-In addition, it can also be used to synthesize 3-aminopyrazole acyl compounds required for various studies.
Method:
-The preparation of acid ethyl ester is usually obtained by reacting 3-aminopyrazole with ethyl formate under alkaline conditions.
-Reaction Ethyl formate is added to the solution of 3-aminopyrazole, and a base is added to promote the reaction.
-After the reaction is completed, the target product is obtained through steps such as acidification and crystallization.
Safety Information:
-acid ethyl ester is irritating and corrosive.
-After contact with skin and eyes, rinse immediately with plenty of water and seek medical help.
-Good ventilation measures should be taken during operation to avoid inhalation and contact.
-Store away from high temperature, fire and oxidant.
-Please follow the chemical safety procedures for use.
Last Update：2024-04-10 22:29:15
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Product Name: 5-Amino-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester Visit Supplier Webpage Request for quotationCAS: 19750-02-8
Tel: +86-18821248368
Email: Int06@meryer.com
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Product Name: 5-Amino-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester Visit Supplier Webpage Request for quotationCAS: 19750-02-8
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