199871-63-1

199871-63-1 - Names and Identifiers

Name	8-Methoxyquinoline-5-carboxylic acid
Synonyms	5-Carboxy-8-methoxyquinoline 8-Methoxyquinoline-5-carboxylic acid 8-METHOXYQUINOLINE-5-CARBOXYLIC ACID N-(3,5-Dichloropyridin-4-yl)-8-methoxyquinoline-5-carboxamide 5-Quinolinecarboxamide, N-(3,5-dichloro-4-pyridinyl)-8-methoxy-
CAS	199871-63-1
InChI	InChI=1/C11H9NO3/c1-15-9-5-4-8(11(13)14)7-3-2-6-12-10(7)9/h2-6H,1H3,(H,13,14)

199871-63-1 - Physico-chemical Properties

Molecular Formula	C16H11Cl2N3O2
Molar Mass	348.18
Density	1.470±0.06 g/cm3(Predicted)
Boling Point	444.2±45.0 °C(Predicted)
Flash Point	198.192°C
Vapor Presure	0mmHg at 25°C
pKa	9.21±0.70(Predicted)
Storage Condition	2-8℃
Refractive Index	1.648

199871-63-1 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
HS Code	29339900

199871-63-1 - Introduction

acid is an organic compound with the formula C11H9NO3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: acid is a white crystalline solid.
-Solubility: Soluble in some organic solvents such as ether, chloroform and dimethyl sulfoxide, but insoluble in water.
-Chemical properties: The compound has a formic acid group and quinoline ring structure, and has a certain acidity.

Use:
-acid, as an intermediate in organic synthesis, has a wide range of applications in the fields of medicine, pesticides and dyes. It is an important raw material for the synthesis of quinolones, which have a broad spectrum of antibacterial and antiparasitic activities, so they are widely used in drug development.

Method:
The common synthesis method of acid is to use quinoline-5-carboxylic acid and methanol for esterification. First, Quinoline -5-formic acid and methanol are added into the reactor, and the esterification reaction is carried out under the action of acid catalyst to produce acid.

Safety Information:
-or acid is a chemical, be sure to pay attention to safe operation. Wear appropriate personal protective equipment such as lab gloves, goggles, and lab coats.
-Avoid contact with skin and eyes. If there is contact, rinse immediately with plenty of water for at least 15 minutes, and seek medical attention in time.
-When performing laboratory synthesis, place it in a well-ventilated place to avoid breathing its vapor.
-Storage should be sealed, dry, and away from fire and oxidizing agents.

Last Update：2024-04-09 21:01:54