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2,4,6-trifluoroacetophenone

2,4,6-trifluoroacetophenone

CAS: 51788-77-3

Molecular Formula: C8H5F3O

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2,4,6-trifluoroacetophenone - Names and Identifiers

Name 2,4,6-trifluoroacetophenone
Synonyms 2,4,6-trifluoroacetophenone
2,4,6-TRIFLUOROACETOPHENONE
2',4',6'-trifluoroacetophenone
2',4',6'-TRIFLUOROACETOPHENONE
1-(2,4,6-trifluorophenyl)ethanone
1-(2,4,6-TRIFLUORO-PHENYL)-ETHANONE
Ethanone, 1-(2,4,6-trifluorophenyl)-
1-(4-fluoro-2-methoxyphenyl)ethanone
1-(2,4-difluorophenyl)-2-fluoroethan-1-one
CAS 51788-77-3
InChI InChI=1/C8H5F3O/c1-4(12)8-6(10)2-5(9)3-7(8)11/h2-3H,1H3

2,4,6-trifluoroacetophenone - Physico-chemical Properties

Molecular FormulaC8H5F3O
Molar Mass174.12
Density1.303±0.06 g/cm3(Predicted)
Boling Point190°C
Flash Point62.1°C
Water SolubilitySlightly soluble in water.
Vapor Presure0.961mmHg at 25°C
Storage ConditionSealed in dry,Room Temperature
Refractive Index1.473
MDLMFCD00061194

2,4,6-trifluoroacetophenone - Risk and Safety

Risk Codes36/37/38 - Irritating to eyes, respiratory system and skin.
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S37 - Wear suitable gloves.
HS Code29147000
Hazard NoteIrritant/Flammable
Hazard ClassIRRITANT

2,4,6-trifluoroacetophenone - Introduction

2,4,6-trifluoroacetophenone is an organic compound with the chemical formula C8H5F3O. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 2,4,6-trifluoroacetophenone is a colorless or slightly yellow liquid.
-Solubility: It is soluble in many organic solvents, such as ethanol, ether and dichloromethane.
-Boiling point: Its boiling point is about 112-113 ℃.
-Density: Its density is about 1.376g/cm³.

Use:
-Chemical synthesis: 2,4,6-trifluoroacetophenone can be used as a reagent in organic synthesis, and is often used to synthesize other organic compounds, such as drugs and dyes.
-Cosmetics: In cosmetics, it can be used as a fragrance ingredient to give the product a unique aroma.
-Medicine: The compound has certain application value in drug research and development.

Preparation Method:
2,4,6-trifluoroacetophenone can be synthesized by the following steps:
-The first step: React acetophenone with trifluoroacetic acid to generate 2,4-difluoroacetophenone.
-The second step: 2,4-difluoroacetophenone is reacted with fluorine gas under the catalysis of sulfuric acid to obtain 2,4,6-trifluoroacetophenone.

Safety Information:
- 2,4,6-trifluoroacetophenone is a chemical that is potentially dangerous.
-It may cause irritation and damage to the eyes, skin and respiratory system, and direct contact should be avoided.
-Wear personal protective equipment such as gloves, goggles and masks during use and operate in a well-ventilated area.
-The compound should be stored and handled properly and disposed of in accordance with relevant regulations.

IMPORTANT: When using and handling any chemicals, please refer to the relevant safety information and operating manuals, and follow the correct operating procedures and personal protective measures.
Last Update:2024-04-09 02:00:46
2,4,6-trifluoroacetophenone
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