2,4-Lutidine
2,4-Lutidine
CAS: 108-47-4
Molecular Formula: C7H9N
2,4-Lutidine - Names and Identifiers
| Name | 2,4-Lutidine |
| Synonyms | 2,4-Lutidine 2,4-Dimethylpyridine Pyridine,2,4-dimethyl- alpha,gamma-Dimethylpyridine 2,4-DIMETHYLPYRIDINE FOR SYNTHESIS 2,4-DIMETHYLPYRIDINE(2,4-LUTIDINE) |
| CAS | 108-47-4 |
| EINECS | 203-586-8 |
| InChIKey | JYYNAJVZFGKDEQ-UHFFFAOYSA-N |
2,4-Lutidine - Physico-chemical Properties
| Molecular Formula | C7H9N |
| Molar Mass | 107.15 |
| Density | 0.927 g/mL at 25 °C (lit.) |
| Melting Point | -60 °C (lit.) |
| Boling Point | 159 °C (lit.) |
| Flash Point | 99°F |
| JECFA Number | 2151 |
| Water Solubility | 15 g/100 mL (20 ºC) |
| Solubility | 350g/l |
| Vapor Presure | 3.28hPa at 25℃ |
| Appearance | Liquid |
| Color | Colorless to Light yellow to Light orange |
| BRN | 1506 |
| pKa | 6.99(at 25℃) |
| Storage Condition | Flammables area |
| Sensitive | Hygroscopic |
| Refractive Index | n20/D 1.499(lit.) |
| Physical and Chemical Properties | Density: relative density (water = 1) 0.93 appearance colorless liquid, pepper odor vapor pressure 4740kPa/76.3 ℃ flash point 37 ℃ melting point -60.0 ℃ boiling point 157~158 ℃ solubility soluble in water, miscible with most organic solvents stable hazard marker 7 (flammable liquid) |
| Use | Used as raw materials for organic synthesis, organic synthesis, synthesis of drugs and used as solvents |
2,4-Lutidine - Risk and Safety
| Risk Codes | R10 - Flammable R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R25 - Toxic if swallowed R20/21 - Harmful by inhalation and in contact with skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 1992 3/PG 3 |
| WGK Germany | 3 |
| RTECS | OK9400000 |
| FLUKA BRAND F CODES | 8 |
| TSCA | Yes |
| HS Code | 29333999 |
| Hazard Class | 3 |
| Packing Group | III |
2,4-Lutidine - Nature
Open Data Verified Data
colorless liquid with pepper odor. Melting Point -60.0c. Boiling point 157~158 deg C. Vapor pressure 4740kPa/76.3. Flash point 37 °c. Soluble in water, miscible in most organic solvents.
Last Update：2025-06-10 22:55:16
2,4-Lutidine - Application
Open Data Verified Data
used in organic synthesis, synthesis of drugs and as solvents.
Last Update：2025-08-19 16:24:40
2,4-Lutidine - Safety
Open Data Verified Data
- health hazards: inhalation, ingestion, percutaneous absorption. Health hazards: harmful to the body after inhalation, oral or skin absorption. It is strongly irritating to the eyes. After contact can cause Cough, chest pain, Dyspnea, gastrointestinal dysfunction.
- toxicological data and environmental behavior toxicity: moderate toxicity. Acute toxicity: LD50 400 ~ 800mg/kg (rats by mouth). Hazard characteristics: flammable, in case of high heat, open fire or contact with oxidant, there is a risk of combustion explosion. Toxic nitrogen oxide smoke is released by thermal decomposition. Combustion (decomposition) products: carbon monoxide, carbon dioxide, nitrogen oxides.
- Protection Measure respiratory system protection: filter gas mask (half mask) should be worn when possible contact with its vapor. In case of emergency rescue or evacuation, it is recommended to wear an isolated respirator. Eye protection: wear chemical safety glasses. Body Protection: wear adhesive tape to prevent
- poison coat. Hand Protection: wear rubber gloves. Other: no smoking at work site. After work, take a shower and change clothes. Pre-employment and regular medical examinations were carried out. Maintain good hygiene practices.
- first aid measures skin contact: remove contaminated clothing and rinse the skin thoroughly with soap and water. Eye contact: lift the eyelids and rinse thoroughly with plenty of running water or saline for at least 15 min. The patient visited hospital. Inhalation: rapid departure from the scene to fresh air. Keep airway unobstructed. Such as Dyspnea, to the delivery of oxygen. If breathing stops, perform artificial respiration immediately. The patient visited hospital. Ingestion: drink enough warm water to induce vomiting.
Last Update：2022-01-01 10:53:10
2,4-Lutidine - Reference Information
| FEMA | 4389 | 2,4-DIMETHYLPYRIDINE |
| LogP | 1.9 |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Use | It is used as an intermediate of medicine, insecticide, rubber catalyst and analytical reagent. organic synthesis and pesticide, pharmaceutical intermediates used in organic synthesis, synthesis of drugs and used as solvent used as raw materials in organic synthesis |
| production method | is mainly recovered from coal coking by-products. Pyridine and its homologs are widely distributed in crude coking chemicals. About 23% of lutidine is found in coke oven gas, 22% in crude benzene and 55% in tar. |
| category | flammable liquid |
| toxicity grade | high toxicity |
| Acute toxicity | oral-rat LD50: 200 mg/kg |
| flammability hazard characteristics | flammable in case of open flame, high temperature and oxidant; toxic nitric oxide gas |
| storage and transportation characteristics | The warehouse is ventilated and dried at low temperature; Stored separately from oxidants and acids |
| extinguishing agent | dry powder, dry sand, carbon dioxide, foam, 1211 extinguishing agent |
Last Update：2024-04-09 15:16:45
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