2-Amino-5-formylthiazole
2-Amino-5-formylthiazole
CAS: 1003-61-8
Molecular Formula: C4H4N2OS
2-Amino-5-formylthiazole - Names and Identifiers
| Name | 2-Amino-5-formylthiazole |
| Synonyms | 2-AMINO-5-FORMYLTHIAZOLE 2-Amino-5-formylthiazole 2-Amino-5-formyl-1,3-thiazole 2-Aminothiazole-5-carbadehyde 2-AMINOTHIAZOLE-5-CARBALDEHYDE 2-AMINOTHIAZOLE-5-CARBOXALDEHYDE 2-amino-1,3-thiazole-5-carbaldehyde |
| CAS | 1003-61-8 |
| InChI | InChI=1/C4H4N2OS/c5-4-6-1-3(2-7)8-4/h1-2H,(H2,5,6) |
| InChIKey | HZKMBJCDAXLMDN-UHFFFAOYSA-N |
2-Amino-5-formylthiazole - Physico-chemical Properties
| Molecular Formula | C4H4N2OS |
| Molar Mass | 128.15 |
| Density | 1.488±0.06 g/cm3(Predicted) |
| Melting Point | 122-132°C |
| Boling Point | 316.3±15.0 °C(Predicted) |
| Flash Point | 145.1°C |
| Vapor Presure | 0.000413mmHg at 25°C |
| pKa | 3.16±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Sensitive | Air Sensitive |
| Refractive Index | 1.712 |
| MDL | MFCD02179570 |
| Physical and Chemical Properties | Storage Conditions: Keep Cold sensitivity: Air Sensitive WGK Germany:3 |
2-Amino-5-formylthiazole - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| HS Code | 29349990 |
| Hazard Note | Irritant/Keep Cold |
| Hazard Class | IRRITANT |
2-Amino-5-formylthiazole - Introduction
2-Amino-5-formylthiazole (2-Amino-5-formylthiazole) is an organic compound with the chemical formula C4H4N2OS.
Nature:
- 2-Amino -5-aldehyde thiazole is a colorless to slightly yellow crystalline or powdery solid.
-It is slightly soluble in water and soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
-The compound is weakly acidic.
Use:
- 2-amino -5-aldehyde thiazole is widely used in organic synthesis as a synthetic intermediate.
-It can be used to synthesize other compounds, such as organic fluorescent dyes, biologically active molecules, etc.
-It can also be used as a ligand in coordination chemistry to participate in metal ion coordination reactions.
Preparation Method:
The preparation method of -2-amino -5-aldehyde thiazole is mainly obtained by N-deprotection or N-defunctional reaction of thiazole.
-A commonly used synthesis method is to react thiazole with N-methyl-N-nitroglycine ester, and deprotection under appropriate conditions to obtain 2-amino-5-aldehydyl thiazole.
Safety Information:
- 2-amino -5-aldehyde thiazole compounds are less toxic and corrosive to human body.
-During operation and storage, avoid contact with harmful substances such as strong oxidants and strong acids.
-When using this compound, wear protective gloves and protective glasses to avoid inhaling its dust or touching your skin.
-In case of accidental contact or inhalation, flush with plenty of water and seek medical help.
Nature:
- 2-Amino -5-aldehyde thiazole is a colorless to slightly yellow crystalline or powdery solid.
-It is slightly soluble in water and soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
-The compound is weakly acidic.
Use:
- 2-amino -5-aldehyde thiazole is widely used in organic synthesis as a synthetic intermediate.
-It can be used to synthesize other compounds, such as organic fluorescent dyes, biologically active molecules, etc.
-It can also be used as a ligand in coordination chemistry to participate in metal ion coordination reactions.
Preparation Method:
The preparation method of -2-amino -5-aldehyde thiazole is mainly obtained by N-deprotection or N-defunctional reaction of thiazole.
-A commonly used synthesis method is to react thiazole with N-methyl-N-nitroglycine ester, and deprotection under appropriate conditions to obtain 2-amino-5-aldehydyl thiazole.
Safety Information:
- 2-amino -5-aldehyde thiazole compounds are less toxic and corrosive to human body.
-During operation and storage, avoid contact with harmful substances such as strong oxidants and strong acids.
-When using this compound, wear protective gloves and protective glasses to avoid inhaling its dust or touching your skin.
-In case of accidental contact or inhalation, flush with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15
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