2-Bromo-6-methyl-3-nitropyridine
2-Bromo-6-methyl-3-nitropyridine
CAS: 374633-31-5
Molecular Formula: C6H5BrN2O2
2-Bromo-6-methyl-3-nitropyridine - Names and Identifiers
2-Bromo-6-methyl-3-nitropyridine - Physico-chemical Properties
| Molecular Formula | C6H5BrN2O2 |
| Molar Mass | 217.02 |
| Density | 1.709g/cm3 |
| Boling Point | 265.2°C at 760 mmHg |
| Flash Point | 114.2°C |
| Vapor Presure | 0.0152mmHg at 25°C |
| Appearance | Solid |
| Color | Off-white |
| Storage Condition | 2-8°C |
| Refractive Index | 1.599 |
2-Bromo-6-methyl-3-nitropyridine - Risk and Safety
| Hazard Class | IRRITANT |
2-Bromo-6-methyl-3-nitropyridine - Introduction
It is an organic compound with the chemical formula C7H6BrN3O2. The following is a description of its nature, use, preparation and safety information:
Nature:
is a yellow crystalline solid. It is a non-volatile solid at room temperature and has low solubility. It has a melting point of about 106-108°C and a boiling point of about 306°C. It gradually decomposes in the solvent and is sensitive to light.
Use:
is an important organic synthesis intermediates. It is often used in the synthesis of drugs, dyes and other organic compounds. Because it can be substituted with the ortho group, it has a certain activity in organic reactions.
Preparation Method:
A common preparation method is to synthesize phenols through ortho-sulfonation and substitution reactions. First, 3-nitropyridine is reacted with o-sulfonyl chloride to form an ammonium o-sulfonate salt. Then, the ortho-sulfonic acid ammonium salt is reacted with chlorite bromide to form phosphonium chloride under basic conditions.
Safety Information:
It is an organic compound, and you need to pay attention to safety during use or preparation. It may be irritating to the respiratory tract, eyes and skin, so appropriate personal protective equipment should be worn during operation. In addition, it also has a certain toxicity, should avoid direct exposure to the human body. During storage and handling, care should be taken to avoid contact with oxidants or flammable materials to avoid fire or explosion. For the specific use and handling of chemicals, follow the appropriate safety practices.
Nature:
is a yellow crystalline solid. It is a non-volatile solid at room temperature and has low solubility. It has a melting point of about 106-108°C and a boiling point of about 306°C. It gradually decomposes in the solvent and is sensitive to light.
Use:
is an important organic synthesis intermediates. It is often used in the synthesis of drugs, dyes and other organic compounds. Because it can be substituted with the ortho group, it has a certain activity in organic reactions.
Preparation Method:
A common preparation method is to synthesize phenols through ortho-sulfonation and substitution reactions. First, 3-nitropyridine is reacted with o-sulfonyl chloride to form an ammonium o-sulfonate salt. Then, the ortho-sulfonic acid ammonium salt is reacted with chlorite bromide to form phosphonium chloride under basic conditions.
Safety Information:
It is an organic compound, and you need to pay attention to safety during use or preparation. It may be irritating to the respiratory tract, eyes and skin, so appropriate personal protective equipment should be worn during operation. In addition, it also has a certain toxicity, should avoid direct exposure to the human body. During storage and handling, care should be taken to avoid contact with oxidants or flammable materials to avoid fire or explosion. For the specific use and handling of chemicals, follow the appropriate safety practices.
Last Update：2024-04-09 21:04:16
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