2-Cyano-6-fluoropyridine
2-Cyano-6-fluoropyridine
CAS: 3939-15-9
Molecular Formula: C6H3FN2
2-Cyano-6-fluoropyridine - Names and Identifiers
2-Cyano-6-fluoropyridine - Physico-chemical Properties
| Molecular Formula | C6H3FN2 |
| Molar Mass | 122.1 |
| Density | 1.24 |
| Melting Point | 31-35 °C |
| Boling Point | 234℃ |
| Flash Point | 95℃ |
| Water Solubility | Insoluble in water. |
| Vapor Presure | 0.054mmHg at 25°C |
| pKa | -5.98±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.509 |
| MDL | MFCD09263323 |
2-Cyano-6-fluoropyridine - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN3439 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Class | 6.1 |
| Packing Group | III |
2-Cyano-6-fluoropyridine - Introduction
2-Cyano-6-fluoropyridine is an organic compound with the chemical formula C6H3FN2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow crystalline solid
-Melting point: 42-44°C
-Boiling point: 150°C
-Solubility: Soluble in organic solvents such as ethanol, chloroform and ether
Use:
2-Cyano-6-fluoropyridine, as an organic synthesis intermediate, has a wide range of applications in the field of organic synthesis:
-Used as a synthetic raw material in the pharmaceutical field, for the synthesis of drugs and bioactive molecules
-Used as a synthetic raw material in the field of pesticides, used in the synthesis of pesticides and herbicides
-in organic synthesis reaction, can be used as acylation reagent, hydrogenation catalyst, reducing reagent, etc
-For the synthesis of organic light-emitting diodes (OLEDs) and other electronic devices
Preparation Method:
The synthesis of 2-Cyano-6-fluoropyridine is usually obtained by the following reaction:
-Reaction of 6-fluoropyridine with potassium cyanide to generate 5-fluoro-2-pyridinecarbonitrile
-Reaction of 5-fluoro-2-pyridinecarbonitrile with nitrosyl chloride to form 2-Cyano-6-fluoropyridine
Safety Information:
2-Cyano-6-fluoropyridine is generally relatively safe when used and stored correctly. But still need to pay attention to the following safety matters:
-Wear appropriate protective equipment such as gloves, goggles and protective clothing during operation
-Avoid inhalation, ingestion, or contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help
-During storage and transportation, pay attention to avoid contact with acids, alkalis, oxidants and combustibles to prevent the risk of fire and explosion
Nature:
-Appearance: Colorless to light yellow crystalline solid
-Melting point: 42-44°C
-Boiling point: 150°C
-Solubility: Soluble in organic solvents such as ethanol, chloroform and ether
Use:
2-Cyano-6-fluoropyridine, as an organic synthesis intermediate, has a wide range of applications in the field of organic synthesis:
-Used as a synthetic raw material in the pharmaceutical field, for the synthesis of drugs and bioactive molecules
-Used as a synthetic raw material in the field of pesticides, used in the synthesis of pesticides and herbicides
-in organic synthesis reaction, can be used as acylation reagent, hydrogenation catalyst, reducing reagent, etc
-For the synthesis of organic light-emitting diodes (OLEDs) and other electronic devices
Preparation Method:
The synthesis of 2-Cyano-6-fluoropyridine is usually obtained by the following reaction:
-Reaction of 6-fluoropyridine with potassium cyanide to generate 5-fluoro-2-pyridinecarbonitrile
-Reaction of 5-fluoro-2-pyridinecarbonitrile with nitrosyl chloride to form 2-Cyano-6-fluoropyridine
Safety Information:
2-Cyano-6-fluoropyridine is generally relatively safe when used and stored correctly. But still need to pay attention to the following safety matters:
-Wear appropriate protective equipment such as gloves, goggles and protective clothing during operation
-Avoid inhalation, ingestion, or contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help
-During storage and transportation, pay attention to avoid contact with acids, alkalis, oxidants and combustibles to prevent the risk of fire and explosion
Last Update：2024-04-09 15:17:57
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View History
2-Cyano-6-fluoropyridine
3-(4-NITROPHENOXY)PROPIONIC ACID ---POWDER PURE---
1-NAPHTHOL-4-SULFONIC ACID SODIUM SALT
14-Amino-tetradecanoic acid
N-ACETYLNEURAMINATE PYRUVATE LYASE
1,2-Cyclohexanediol diglycidyl ether
马来酰亚胺聚乙二醇羧基
Cocoamidopropyl dimethyl betaine
2-甲基-2-乙烯基噁丙环
β-1,3-Glucan
3-(4-NITROPHENOXY)PROPIONIC ACID ---POWDER PURE---
1-NAPHTHOL-4-SULFONIC ACID SODIUM SALT
14-Amino-tetradecanoic acid
N-ACETYLNEURAMINATE PYRUVATE LYASE
1,2-Cyclohexanediol diglycidyl ether
马来酰亚胺聚乙二醇羧基
Cocoamidopropyl dimethyl betaine
2-甲基-2-乙烯基噁丙环
β-1,3-Glucan