2-Fluoro-3-nitropyridine
2-Fluoro-3-nitropyridine
CAS: 1480-87-1
Molecular Formula: C5H3FN2O2
2-Fluoro-3-nitropyridine - Names and Identifiers
| Name | 2-Fluoro-3-nitropyridine |
| Synonyms | uoro-3-nitropyridine 2-Fluoro-3-nitropyri 2-FLUORO-3-NITROPYRIDINE 2-Fluoro-3-nitropyridine 2-Fluoro-3-nitrylpyridine Pyridine, 2-fluoro-3-nitro- 3-bromo-2-fluoro-5-trifluoromethyl ryridine |
| CAS | 1480-87-1 |
| EINECS | 675-588-0 |
| InChI | InChI=1/C5H3FN2O2/c6-5-4(8(9)10)2-1-3-7-5/h1-3H |
2-Fluoro-3-nitropyridine - Physico-chemical Properties
| Molecular Formula | C5H3FN2O2 |
| Molar Mass | 142.09 |
| Density | 1.439±0.06 g/cm3(Predicted) |
| Melting Point | 18℃ |
| Boling Point | 110℃/10mm |
| Flash Point | 103.842°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 0.039mmHg at 25°C |
| Appearance | Crystalline powder |
| Color | Yellow |
| pKa | -4.47±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.5300 to 1.5340 |
| MDL | MFCD03095068 |
2-Fluoro-3-nitropyridine - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| Hazard Note | Toxic |
| Hazard Class | IRRITANT |
2-Fluoro-3-nitropyridine - Introduction
2-Fluoro-3-nitropyridine is an organic compound with the chemical formula C5H3FN2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-Fluoro-3-nitropyridine is a colorless to pale yellow crystalline powder;
-Melting point: About 80-82 ° C;
-Boiling point: About 251-252 ° C;
-May decompose or explode at high temperatures.
Use:
- 2-Fluoro-3-nitropyridine is commonly used in organic synthesis and pharmaceutical research;
-It can be used as a synthetic raw material for pesticides, dyes, explosives intermediates, etc;
-It can also be used in organic synthesis reactions, such as substitution reactions and fluorination reactions.
Method:
- 2-Fluoro-3-nitropyridine has many preparation methods. Here is one of the common methods:
1. Reacting 2,3-dibromopyridine with silver nitrite to obtain 2-nitro-3-bromopyridine;
2. 2-nitro-3-bromopyridine reacts with hydrogen fluoride under alkaline conditions to generate 2-Fluoro-3-nitropyridine.
Safety Information:
- 2-Fluoro-3-nitropyridine is an organic compound with certain toxicity and flammability;
-in the operation need to pay attention to protective measures, such as wearing protective glasses, gloves, keep good ventilation;
-Avoid contact with skin, eyes and respiratory tract;
-If taken by mistake or inhaled, seek medical attention immediately.
Nature:
-Appearance: 2-Fluoro-3-nitropyridine is a colorless to pale yellow crystalline powder;
-Melting point: About 80-82 ° C;
-Boiling point: About 251-252 ° C;
-May decompose or explode at high temperatures.
Use:
- 2-Fluoro-3-nitropyridine is commonly used in organic synthesis and pharmaceutical research;
-It can be used as a synthetic raw material for pesticides, dyes, explosives intermediates, etc;
-It can also be used in organic synthesis reactions, such as substitution reactions and fluorination reactions.
Method:
- 2-Fluoro-3-nitropyridine has many preparation methods. Here is one of the common methods:
1. Reacting 2,3-dibromopyridine with silver nitrite to obtain 2-nitro-3-bromopyridine;
2. 2-nitro-3-bromopyridine reacts with hydrogen fluoride under alkaline conditions to generate 2-Fluoro-3-nitropyridine.
Safety Information:
- 2-Fluoro-3-nitropyridine is an organic compound with certain toxicity and flammability;
-in the operation need to pay attention to protective measures, such as wearing protective glasses, gloves, keep good ventilation;
-Avoid contact with skin, eyes and respiratory tract;
-If taken by mistake or inhaled, seek medical attention immediately.
Last Update：2024-04-09 19:05:46
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