2-Iodo-5-hydroxypyridine
2-Iodo-5-hydroxypyridine
CAS: 129034-38-4
Molecular Formula: C5H4INO
2-Iodo-5-hydroxypyridine - Names and Identifiers
| Name | 2-Iodo-5-hydroxypyridine |
| Synonyms | iodopyridin-3-ol 6-Iodo-3-pyridinol 6-Iodopyridin-3-ol 3-Pyridinol, 6-iodo- 5-Hydroxy-2-iodopyridine 2-Iodo-5-hydroxypyridine |
| CAS | 129034-38-4 |
| InChI | InChI=1/C5H4INO/c6-5-2-1-4(8)3-7-5/h1-3,8H |
2-Iodo-5-hydroxypyridine - Physico-chemical Properties
| Molecular Formula | C5H4INO |
| Molar Mass | 221 |
| Density | 2.142±0.06 g/cm3(Predicted) |
| Melting Point | 149-151 °C |
| Boling Point | 399.7±27.0 °C(Predicted) |
| Flash Point | 195.52°C |
| Solubility | Acetone (Slightly), DMSO (Slightly) |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Solid |
| Color | Light Beige |
| pKa | 8.79±0.10(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.683 |
2-Iodo-5-hydroxypyridine - Introduction
2-iodine -5-hydroxyl pyridine, chemical formula C5H3IN2O, is an organic compound. It is a white solid with a special smell. The following are some information about the properties, uses, preparation and safety of 2-iodo-5-hydroxypyridine:
Nature:
1. Appearance: white solid
2. molecular weight: 222.99g/mol
3. Melting point: 148-150°C
4. Solubility: Soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons, insoluble in water.
Use:
1. chemical synthesis: 2-iodine -5-hydroxyl pyridine can be used as an important intermediate in organic synthesis, for the synthesis of other organic compounds.
2. Drug research: Due to its special structure, 2-iodo-5-hydroxypyridine has certain application potential in the field of drug research, such as as an antibacterial agent and a precursor of antiviral drugs.
Preparation Method:
The preparation of 2-iodo-5-hydroxypyridine is usually carried out by the following chemical reactions:
Under alkaline conditions, 2-pyridinecarboxaldehyde is reacted with iodo hydrogen acid to obtain the corresponding 2-(iodomethyl)-5-hydroxypyridine compound. The final product 2-iodo-5-hydroxypyridine is then obtained by reduction or other reactions.
Safety Information:
1. 2-Iodo-5-hydroxypyridine should be used in a laboratory or industrial environment and comply with relevant safety procedures.
2. It may be irritating to the eyes, skin and respiratory tract. Wear appropriate personal protective equipment (such as gloves, goggles and protective mask) when exposed.
3. should be stored in a sealed container, avoid contact with air, moisture and light.
4. in the treatment of 2-iodine -5-hydroxyl pyridine, should avoid direct contact with the skin and inhalation of its volatiles, maintain good ventilation conditions. In case of contact, rinse immediately with plenty of water and seek medical help.
Nature:
1. Appearance: white solid
2. molecular weight: 222.99g/mol
3. Melting point: 148-150°C
4. Solubility: Soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons, insoluble in water.
Use:
1. chemical synthesis: 2-iodine -5-hydroxyl pyridine can be used as an important intermediate in organic synthesis, for the synthesis of other organic compounds.
2. Drug research: Due to its special structure, 2-iodo-5-hydroxypyridine has certain application potential in the field of drug research, such as as an antibacterial agent and a precursor of antiviral drugs.
Preparation Method:
The preparation of 2-iodo-5-hydroxypyridine is usually carried out by the following chemical reactions:
Under alkaline conditions, 2-pyridinecarboxaldehyde is reacted with iodo hydrogen acid to obtain the corresponding 2-(iodomethyl)-5-hydroxypyridine compound. The final product 2-iodo-5-hydroxypyridine is then obtained by reduction or other reactions.
Safety Information:
1. 2-Iodo-5-hydroxypyridine should be used in a laboratory or industrial environment and comply with relevant safety procedures.
2. It may be irritating to the eyes, skin and respiratory tract. Wear appropriate personal protective equipment (such as gloves, goggles and protective mask) when exposed.
3. should be stored in a sealed container, avoid contact with air, moisture and light.
4. in the treatment of 2-iodine -5-hydroxyl pyridine, should avoid direct contact with the skin and inhalation of its volatiles, maintain good ventilation conditions. In case of contact, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 15:17:51
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View History
2-Iodo-5-hydroxypyridine
108-11-2
8048-31-5
64379-72-2
Ethyl carprylate
163795-75-3
Siosecin
Ammonium Phosphomolybdate Trihydrate
GLYCINE-NHME HCL
NSC 4649
108-11-2
8048-31-5
64379-72-2
Ethyl carprylate
163795-75-3
Siosecin
Ammonium Phosphomolybdate Trihydrate
GLYCINE-NHME HCL
NSC 4649