2-METHOXYTETRAFLUOROPROPIONAMIDE

2-METHOXYTETRAFLUOROPROPIONAMIDE - Names and Identifiers

Name	2-METHOXYTETRAFLUOROPROPIONAMIDE
Synonyms	2-METHOXYTETRAFLUOROPROPIONAMIDE 2-Methoxy-2,3,3,3-tetrafluoropropanamide 2-Methoxy-2,3,3,3-tetrafluoropropionamide Propanamide, 2,3,3,3-tetrafluoro-2-methoxy-
CAS	10186-65-9
InChI	InChI=1/C4H5F4NO2/c1-11-3(5,2(9)10)4(6,7)8/h1H3,(H2,9,10)

2-METHOXYTETRAFLUOROPROPIONAMIDE - Physico-chemical Properties

Molecular Formula	C4H5F4NO2
Molar Mass	175.08
Density	1.416g/cm³
Boling Point	191.9°C at 760 mmHg
Flash Point	69.9°C
Vapor Presure	0.502mmHg at 25°C
Storage Condition	Room Temprature
Refractive Index	1.348

2-METHOXYTETRAFLUOROPROPIONAMIDE - Introduction

2-Methoxytetrafluoropropionamide, also known as MeO-TFPA, is an organic compound. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: 2-methoxytetrafluoropropionamide is a colorless or light yellow crystalline powder.
-Melting point: The melting point is about 55-59°C.
-Solubility: Soluble in some organic solvents such as chloroform, dichloromethane and ethanol, almost insoluble in water.
-chemical properties: it is a strong acidic compounds, can react with alkali to generate the corresponding salts.

Use:
-2-Methoxytetrafluoropropionamide is an important intermediate in organic synthesis. It is widely used in the field of drug synthesis, pesticide synthesis and dye synthesis.
-It can be used as a fluorination reagent and play the role of fluorination or tetrafluoropropionic acid protection in organic reactions.
-2-methoxytetrafluoropropanamide can also be used for fluorination reactions in organic synthesis, such as the synthesis of high-fluorine compounds through fluorination reactions.

Preparation Method:
The preparation method of 2-methoxytetrafluoropropionamide can be through the following steps:
1. react methoxy amine with tetrafluoropropionyl chloride to generate tetrafluoropropionamide methyl ester.
2. The tetrafluoropropionamide methyl ester reacts with methanol under alkaline conditions to generate 2-methoxytetrafluoropropionamide.

Safety Information:
There is limited safety information on 2-methoxytetrafluoropropionamide, but based on the similar nature of the chemical, the following should be noted:
-2-methoxytetrafluoropropionamide may be irritating to eyes and skin, please use appropriate personal protective equipment.
-Avoid inhaling the substance in the form of gas, dust or haze, and avoid contact with skin and eyes.
-If contact occurs, immediately flush the affected area with plenty of water and seek medical help.
-Store 2-methoxytetrafluoropropionamide well away from heat sources and open flames.
-When using and storing, please follow the local safety procedures and regulations.

Last Update：2024-04-09 21:54:55