2-Piperidinecarboxylic
2-Piperidinecarboxylic acid methyl ester
CAS: 41994-45-0
Molecular Formula: C7H13NO2
2-Piperidinecarboxylic - Names and Identifiers
2-Piperidinecarboxylic - Physico-chemical Properties
| Molecular Formula | C7H13NO2 |
| Molar Mass | 143.18 |
| Density | 1.021±0.06 g/cm3(Predicted) |
| Boling Point | 193.8±33.0 °C(Predicted) |
| pKa | 8.27±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
2-Piperidinecarboxylic - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| HS Code | 29333990 |
2-Piperidinecarboxylic - Introduction
2-Piperidinecarboxylic acid methyl ester is an organic compound whose chemical formula is C8H15NO2. The following is information about the properties, use, preparation and safety of the compound:
Nature:
- 2-Piperidinecarboxylic acid methyl ester is a colorless liquid with a fragrance-like odor.
-Its melting point is -20°C and boiling point is 220°C.
-The compound is soluble in organic solvents such as ethanol and ether.
Use:
- 2-Piperidinecarboxylic acid methyl ester is commonly used as a reagent or intermediate in organic synthesis reactions.
-It can be used to synthesize drugs containing piperidine skeleton, such as antipsychotic drugs.
Preparation Method:
- 2-Piperidinecarboxylic acid methyl ester can be prepared by the esterification of 2-aminomethylpiperidine and methyl formate.
-The reaction conditions are generally to add a catalyst (such as hydrochloric acid) in a suitable solvent and heat the reaction for a period of time to obtain the product.
Safety Information:
- 2-Piperidinecarboxylic acid methyl ester is generally considered to have low toxicity, but it is still necessary to comply with safe operation procedures.
-When using, care should be taken to avoid contact with skin, eyes and respiratory tract.
-should be in a well-ventilated place to operate, avoid inhalation of its steam.
-Wear appropriate personal protective equipment such as gloves and goggles during handling.
Generally speaking, 2-Piperidinecarboxylic acid methyl ester is a commonly used organic synthesis reagent, which is commonly used in drug synthesis and other fields. When in use, attention should be paid to safe operation to avoid potential hazards.
Nature:
- 2-Piperidinecarboxylic acid methyl ester is a colorless liquid with a fragrance-like odor.
-Its melting point is -20°C and boiling point is 220°C.
-The compound is soluble in organic solvents such as ethanol and ether.
Use:
- 2-Piperidinecarboxylic acid methyl ester is commonly used as a reagent or intermediate in organic synthesis reactions.
-It can be used to synthesize drugs containing piperidine skeleton, such as antipsychotic drugs.
Preparation Method:
- 2-Piperidinecarboxylic acid methyl ester can be prepared by the esterification of 2-aminomethylpiperidine and methyl formate.
-The reaction conditions are generally to add a catalyst (such as hydrochloric acid) in a suitable solvent and heat the reaction for a period of time to obtain the product.
Safety Information:
- 2-Piperidinecarboxylic acid methyl ester is generally considered to have low toxicity, but it is still necessary to comply with safe operation procedures.
-When using, care should be taken to avoid contact with skin, eyes and respiratory tract.
-should be in a well-ventilated place to operate, avoid inhalation of its steam.
-Wear appropriate personal protective equipment such as gloves and goggles during handling.
Generally speaking, 2-Piperidinecarboxylic acid methyl ester is a commonly used organic synthesis reagent, which is commonly used in drug synthesis and other fields. When in use, attention should be paid to safe operation to avoid potential hazards.
Last Update：2024-04-09 02:00:46
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