2-quinolylmethanol
2-quinolylmethanol
CAS: 1780-17-2
Molecular Formula: C10H9NO
2-quinolylmethanol - Names and Identifiers
| Name | 2-quinolylmethanol |
| Synonyms | 2-QUINOLINONE 2-quinolylmethanol RARECHEM AK ML 0556 2-Quinolinemethanol 2-QUINOLINEMETHANOL 2-Quinolinylmethanol 2-QUINOLINYLMETHANOL 2-Quinolineylmethanol QUINOLIN-2-YLMETHANOL quinolin-2-ylmethanol 2-HYDROXYMETHYLQUINOLINE 2-Hydroxymethylquinoline |
| CAS | 1780-17-2 |
| EINECS | 217-225-7 |
| InChI | InChI=1/C10H9NO/c12-7-9-6-5-8-3-1-2-4-10(8)11-9/h1-6,12H,7H2 |
2-quinolylmethanol - Physico-chemical Properties
| Molecular Formula | C10H9NO |
| Molar Mass | 159.18 |
| Density | 1.218±0.06 g/cm3(Predicted) |
| Melting Point | 64 °C |
| Boling Point | 205 °C(Press: 15 Torr) |
| Flash Point | 141.6°C |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.000255mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 14.29±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.667 |
2-quinolylmethanol - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| Hazard Note | Irritant |
2-quinolylmethanol - Introduction
2-quinolylmethanol is an organic compound with the molecular formula C10H9NO. It is a white solid with a special smell. The following is a description of the nature, use, preparation and safety information of 2-quinolylmethanol:
Nature:
2-quinolylmethanol has good thermal stability and solubility, and its solubility in water is low. It is a photosensitive compound that can generate reactive species by ultraviolet light excitation.
Use:
2-quinolylmethanol is often used as a raw material and intermediate in organic synthesis. It can participate in a variety of reactions such as substitution reaction, carboxylic acid esterification reaction, oxidation reaction, etc., for the synthesis of pesticides, drugs and dyes and other organic compounds.
Method:
2-quinolylmethanol can be prepared by the condensation reaction of 2-quinolinecarboxaldehyde and methanol. First, 2-quinolinecarboxaldehyde is reacted with methanol under appropriate conditions to give 2-quinolylmethanol. This process generally requires the presence of a catalyst, such as an amino alcohol or a metal salt catalyst.
Safety Information:
When using and handling 2-quinolylmethanol, you need to pay attention to the following safety precautions:
1. 2-quinolylmethanol is irritating and toxic, and direct contact with skin, eyes and respiratory tract should be avoided.
2. Pay attention to personal protective measures during operation, including wearing appropriate protective glasses, gloves and protective clothing.
3. When operating in a closed environment, adequate ventilation should be provided to avoid the accumulation of vapor.
4. Waste should be handled in accordance with local regulations to avoid discharge into water bodies or the environment.
It is important to use and store 2-quinolylmethanol with care and to follow relevant operating practices and safety standards.
Nature:
2-quinolylmethanol has good thermal stability and solubility, and its solubility in water is low. It is a photosensitive compound that can generate reactive species by ultraviolet light excitation.
Use:
2-quinolylmethanol is often used as a raw material and intermediate in organic synthesis. It can participate in a variety of reactions such as substitution reaction, carboxylic acid esterification reaction, oxidation reaction, etc., for the synthesis of pesticides, drugs and dyes and other organic compounds.
Method:
2-quinolylmethanol can be prepared by the condensation reaction of 2-quinolinecarboxaldehyde and methanol. First, 2-quinolinecarboxaldehyde is reacted with methanol under appropriate conditions to give 2-quinolylmethanol. This process generally requires the presence of a catalyst, such as an amino alcohol or a metal salt catalyst.
Safety Information:
When using and handling 2-quinolylmethanol, you need to pay attention to the following safety precautions:
1. 2-quinolylmethanol is irritating and toxic, and direct contact with skin, eyes and respiratory tract should be avoided.
2. Pay attention to personal protective measures during operation, including wearing appropriate protective glasses, gloves and protective clothing.
3. When operating in a closed environment, adequate ventilation should be provided to avoid the accumulation of vapor.
4. Waste should be handled in accordance with local regulations to avoid discharge into water bodies or the environment.
It is important to use and store 2-quinolylmethanol with care and to follow relevant operating practices and safety standards.
Last Update：2024-04-09 21:01:54
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View History
2-quinolylmethanol
METHYL P-CYANOBENZOATE
DL-2-氨基-1-环己醇
1-氟-2-溴苯
C9 branched alkyl phenol
223137-87-9
二氧化硫标准溶液
3-HYDROXYDIPHENYLAMINE
乙基卡必醇醋酸酯
L-缬氨酸盐酸盐
METHYL P-CYANOBENZOATE
DL-2-氨基-1-环己醇
1-氟-2-溴苯
C9 branched alkyl phenol
223137-87-9
二氧化硫标准溶液
3-HYDROXYDIPHENYLAMINE
乙基卡必醇醋酸酯
L-缬氨酸盐酸盐