20126-59-4 - Names and Identifiers
20126-59-4 - Physico-chemical Properties
| Molecular Formula | C22H22O11
|
| Molar Mass | 462.4 |
| Density | 1.609 |
| Melting Point | 253-255℃ |
| Boling Point | 803.6±65.0 °C(Predicted) |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | Yellow powder |
| pKa | 6.10±0.40(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD20526611 |
| Physical and Chemical Properties | Yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from lemon, geranium bark, chrysanthemum. |
20126-59-4 - Reference
| Reference Show more | 1. Cheng, Tao, et al. "Comparative pharmacokinetics study of icariin and icariside II in rats." Molecules 20.12 (2015): 21274-21286.https://doi.org/10.3390/molecules201219763 2. [IF=4.411] Tao Cheng et al."Comparative Pharmacokinetics Study of Icariin and Icariside II in Rats."Molecules. 2015 Dec;20(12):21274-21286 3. [IF=8.198] Tong Wang et al."High-Speed Countercurrent Chromatography-Based Method for Simultaneous Recovery and Separation of Natural Products from Deep Eutectic Solvent Extracts."Acs Sustain Chem Eng. 2020;8(4):2073–2080 4. [IF=4.411] Yi Li et al."Evaluation of Anti-Inflammatory and Antioxidant Effectsof Chrysanthemum Stem and Leaf Extract on Zebrafish Inflammatory Bowel Disease Model."Molecules. 2022 Jan;27(7):2114 |
20126-59-4 - Introduction
Also known as kaempferol-7-O-glucoside, is a flavonoid found in many plants. Its chemical structure includes a benzene ring and a pyran ring with a glucose group. Its molecular formula is C21H20O11.
It has certain biological activity and pharmacological effects. It is considered to have antioxidant, anti-inflammatory, anti-tumor, antibacterial, antiviral and other effects. Studies have shown that it has an inhibitory effect on a variety of cancer cells and has certain anti-tumor activity.
It can be prepared in a variety of ways, the common method is extraction and isolation from plants. Some common plant sources include tea, cabbage, apple, etc.
Regarding safety information, it is generally considered to be relatively safe when used in food, health products and drugs. However, excessive intake may cause some side effects, such as diarrhea or stomach upset. In addition, for pregnant and lactating women, as well as people with special diseases, it should be used with caution and under the guidance of a doctor.
To sum up, it has certain biological activity and pharmacological effects, and has some potential application value. However, for specific use and dosage, evaluation and medical personnel guidance should be carried out on a case-by-case basis.
Last Update:2024-04-09 21:31:56