203640-27-1
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid
CAS: 203640-27-1
Molecular Formula: C24H20N2O4S2
203640-27-1 - Names and Identifiers
203640-27-1 - Physico-chemical Properties
| Molecular Formula | C24H20N2O4S2 |
| Molar Mass | 464.56 |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| In vitro study | S 3304 is a novel D-tryptophan derivative and a potent, orally active, noncytotoxic Matrix metalloproteinases inhibitor (MMPI). Biochemical studies show that S 3304 most potently inhibits the activities of MMP-2 and MMP-9 but does not inhibit MMP-1, MMP-3, or MMP-7 and may, therefore, lack the musculoskeletal side effects seen with nonspecific inhibitors. |
| In vivo study | In vivo pharmacologic studies have shown that the oral administration of S 3304, at a dose range of 20 to 200 mg/kg, inhibits angiogenesis, artificially induced in mice by the dorsal air-sac method. Similar oral doses of S 3304 result in potent inhibition of metastatic lung colonization of Lewis murine lung carcinoma injected via tail vein and liver metastasis of C-1H human colon cancer implanted into the spleen. |
203640-27-1 - Introduction
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid, also known as ITM-2502, is an organic compound. Its properties are as follows:
1. Appearance: It is a solid powder, which may be yellow or white.
2. Solubility: It is soluble in common organic solvents (such as dimethyl sulfoxide, ethanol and dichloromethane).
3. Use: ITM-2502 is a drug intermediate, mainly used for the synthesis of other pharmaceutical compounds. It may have anti-tumor, anti-inflammatory, anti-microbial activity.
4 preparation method: the preparation method of ITM-2502 is more complex, generally need to use the method of organic synthesis chemical reaction chain.
5. SAFETY INFORMATION: There is currently limited information on the safety and toxicology of ITM-2502, so caution should be used. Observe appropriate laboratory safety practices and follow relevant regulations and guidelines when using or handling the substance. If necessary, further toxicity studies and safety assessments should be conducted.
1. Appearance: It is a solid powder, which may be yellow or white.
2. Solubility: It is soluble in common organic solvents (such as dimethyl sulfoxide, ethanol and dichloromethane).
3. Use: ITM-2502 is a drug intermediate, mainly used for the synthesis of other pharmaceutical compounds. It may have anti-tumor, anti-inflammatory, anti-microbial activity.
4 preparation method: the preparation method of ITM-2502 is more complex, generally need to use the method of organic synthesis chemical reaction chain.
5. SAFETY INFORMATION: There is currently limited information on the safety and toxicology of ITM-2502, so caution should be used. Observe appropriate laboratory safety practices and follow relevant regulations and guidelines when using or handling the substance. If necessary, further toxicity studies and safety assessments should be conducted.
Last Update：2024-04-09 20:49:11
Supplier List
Multiple SpecificationsSpot supply
Product Name: S3304 Request for quotationCAS: 203640-27-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: S 3304 Visit Supplier Webpage Request for quotationCAS: 203640-27-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: S 3304 Visit Supplier Webpage Request for quotationCAS: 203640-27-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: S 3304 Visit Supplier Webpage Request for quotationCAS: 203640-27-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: (R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Visit Supplier Webpage Request for quotation
CAS: 203640-27-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 203640-27-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Multiple SpecificationsSpot supply
Product Name: S3304 Request for quotationCAS: 203640-27-1
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: S 3304 Visit Supplier Webpage Request for quotationCAS: 203640-27-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: S 3304 Visit Supplier Webpage Request for quotationCAS: 203640-27-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: S 3304 Visit Supplier Webpage Request for quotationCAS: 203640-27-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Product Name: (R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Visit Supplier Webpage Request for quotation
CAS: 203640-27-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 203640-27-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
203640-27-1
二乙基二氯化锡
103426-20-6
1609393-90-9
(吡啶)三氯化金
2316733-81-8
15897-81-1
817194-38-0
202191-12-6
1987261-68-6
二乙基二氯化锡
103426-20-6
1609393-90-9
(吡啶)三氯化金
2316733-81-8
15897-81-1
817194-38-0
202191-12-6
1987261-68-6