204322-23-6
Fmoc-L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid
CAS: 204322-23-6
Molecular Formula: C27H22N2O4
204322-23-6 - Names and Identifiers
| Name | Fmoc-L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid |
| Synonyms | FMOC-L-TPI FMOC-TPI-OH Fmoc-L-Tpi-OH FMOC-THNH(3)-OH RARECHEM BK PT 0090 Fmoc-L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid FMOC-L-1,2,3,4-TETRAHYDRONORHARMAN-3-CARBOXYLIC ACID (S)-2-FMOC-1,2,3,4-TETRAHYDRONORHARMANE-3-CARBOXYLIC ACID N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-TRYPTOLINE-3-CARBOXYLIC ACID N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-1,2,3,4-TETRAHYDRONORHAM-3-CARBOXYLIC ACID (3S)-2-[(9H-fluoren-9-ylmethoxy)carbonyl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid |
| CAS | 204322-23-6 |
| InChI | InChI=1/C27H22N2O4/c30-26(31)25-13-21-20-11-5-6-12-23(20)28-24(21)14-29(25)27(32)33-15-22-18-9-3-1-7-16(18)17-8-2-4-10-19(17)22/h1-12,22,25,28H,13-15H2,(H,30,31)/t25-/m0/s1 |
204322-23-6 - Physico-chemical Properties
| Molecular Formula | C27H22N2O4 |
| Molar Mass | 438.47 |
| Density | 1.396±0.06 g/cm3(Predicted) |
| Boling Point | 702.4±60.0 °C(Predicted) |
| Flash Point | 378.6°C |
| Vapor Presure | 1.04E-20mmHg at 25°C |
| pKa | 3.92±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.713 |
204322-23-6 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| WGK Germany | 3 |
| HS Code | 29242990 |
| Hazard Class | IRRITANT |
204322-23-6 - Introduction
Fmoc-L-1,2,3, acid is an organic compound. The following will introduce its nature, use, preparation and safety information.
1. Nature:
Fmoc-L-1,2,3, acid is a solid powder with white or almost white color. Its molecular formula is C22H25NO4 and its molecular weight is 367.44g/mol. It is a photosensitive compound, soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane and N,N-dimethylacetamide (DMF), but insoluble in water.
2. Use:
Fmoc-L-1,2,3, acid is a commonly used protecting group reagent, mainly used for solid phase synthesis and peptide synthesis process of protecting group removal. It can react with amino acid or amino group in peptide segment by acylation reaction to form Fmoc protecting group with protective effect.
3. Preparation method:
Fmoc-L-1,2,3, acid is usually obtained by chemical synthesis. The specific preparation method can refer to the relevant literature.
4. Safety Information:
Fmoc-L-1,2,3, acid is generally relatively safe under normal operating conditions. However, since it is a chemical agent, appropriate protective measures need to be taken. Wear appropriate protective gloves and goggles during operation to avoid contact with skin, eyes and inhalation of dust. During storage, it should be kept in a dry, cool place, away from open flames and heat sources. At the same time, it is also necessary to strictly follow the relevant safety operation procedures. In case of accidental contact or aspiration, rinse immediately with plenty of water and seek medical help.
1. Nature:
Fmoc-L-1,2,3, acid is a solid powder with white or almost white color. Its molecular formula is C22H25NO4 and its molecular weight is 367.44g/mol. It is a photosensitive compound, soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane and N,N-dimethylacetamide (DMF), but insoluble in water.
2. Use:
Fmoc-L-1,2,3, acid is a commonly used protecting group reagent, mainly used for solid phase synthesis and peptide synthesis process of protecting group removal. It can react with amino acid or amino group in peptide segment by acylation reaction to form Fmoc protecting group with protective effect.
3. Preparation method:
Fmoc-L-1,2,3, acid is usually obtained by chemical synthesis. The specific preparation method can refer to the relevant literature.
4. Safety Information:
Fmoc-L-1,2,3, acid is generally relatively safe under normal operating conditions. However, since it is a chemical agent, appropriate protective measures need to be taken. Wear appropriate protective gloves and goggles during operation to avoid contact with skin, eyes and inhalation of dust. During storage, it should be kept in a dry, cool place, away from open flames and heat sources. At the same time, it is also necessary to strictly follow the relevant safety operation procedures. In case of accidental contact or aspiration, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-10 22:29:15
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