205178-80-9
2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one
CAS: 205178-80-9
Molecular Formula: C9H8BrClO
205178-80-9 - Names and Identifiers
205178-80-9 - Physico-chemical Properties
| Molecular Formula | C9H8BrClO |
| Molar Mass | 247.52 |
| Density | 1.524±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 56 °C |
| Boling Point | 312.3±27.0 °C(Predicted) |
| Flash Point | 142.692°C |
| Vapor Presure | 0.001mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.576 |
205178-80-9 - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
205178-80-9 - Introduction
2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one is an organic compound with the molecular formula C10H9BrClO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one as a colorless to pale yellow solid.
-Solubility: Soluble in organic solvents such as ether, ethanol and dichloromethane, insoluble in water.
-Melting point: About 90-94 degrees Celsius.
-Density: about 1.429 g/mL.
Use:
- 2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one reagents and intermediates commonly used in organic synthesis reactions.
-It can be used to synthesize other compounds, such as drugs, dyes and pesticides.
Method:
The preparation method of -2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one can be achieved by the substitution reaction of acetophenone.
-In the reaction, acetophenone is reacted with bromine under acidic conditions, and then ferrous chloride catalyst is added to obtain the target product.
Safety Information:
- 2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one irritating and corrosive.
-use should wear appropriate personal protective equipment, such as chemical gloves, protective glasses, etc.
-Avoid contact with skin, eyes and respiratory tract, avoid swallowing or inhaling.
-In case of contact, rinse immediately with plenty of water and seek medical help.
-During storage and handling, the relevant safety procedures should be strictly observed.
Nature:
-Appearance: 2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one as a colorless to pale yellow solid.
-Solubility: Soluble in organic solvents such as ether, ethanol and dichloromethane, insoluble in water.
-Melting point: About 90-94 degrees Celsius.
-Density: about 1.429 g/mL.
Use:
- 2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one reagents and intermediates commonly used in organic synthesis reactions.
-It can be used to synthesize other compounds, such as drugs, dyes and pesticides.
Method:
The preparation method of -2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one can be achieved by the substitution reaction of acetophenone.
-In the reaction, acetophenone is reacted with bromine under acidic conditions, and then ferrous chloride catalyst is added to obtain the target product.
Safety Information:
- 2-bromo-1-(4-chloro-3-methylphenyl)ethan-1-one irritating and corrosive.
-use should wear appropriate personal protective equipment, such as chemical gloves, protective glasses, etc.
-Avoid contact with skin, eyes and respiratory tract, avoid swallowing or inhaling.
-In case of contact, rinse immediately with plenty of water and seek medical help.
-During storage and handling, the relevant safety procedures should be strictly observed.
Last Update：2024-04-09 15:17:54
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