205526-36-9
(S)-N-FMOC-3-Cyanophenylalanine
CAS: 205526-36-9
Molecular Formula: C25H20N2O4
205526-36-9 - Names and Identifiers
| Name | (S)-N-FMOC-3-Cyanophenylalanine |
| Synonyms | RARECHEM BK PT 0153 Fmoc-L-3-Cyanophenylalanine FMOC-L-3-CYANOPHENYLALANINE Fmoc-3-Cyano-L-phenylalanine FMOC-3-CYANO-L-PHENYLALANINE N-FMOC-M-CYANO-L-PHENYLALANINE (S)-N-FMOC-3-Cyanophenylalanine (S)-N-FMOC-3-CYANOPHENYLALANINE N-(9-FLUORENYLMETHOXYCARBONYL)-3-CYANOPHENYL-L-ALANINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-M-CYANO-L-PHENYLALANINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-3-CYANO-L-PHENYLALANINE (S)-2-(FLUORENYLMETHOXYCARBONYLAMINO)-3-(3-CYANOPHENYL)PROPANOIC ACID |
| CAS | 205526-36-9 |
| InChI | InChI=1/C25H20N2O4/c26-14-17-7-5-6-16(12-17)13-23(24(28)29)27-25(30)31-15-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,22-23H,13,15H2,(H,27,30)(H,28,29)/t23-/m0/s1 |
205526-36-9 - Physico-chemical Properties
| Molecular Formula | C25H20N2O4 |
| Molar Mass | 412.44 |
| Density | 1.2691 (rough estimate) |
| Melting Point | 115.6 °C |
| Boling Point | 531.88°C (rough estimate) |
| Flash Point | 359.5°C |
| Vapor Presure | 6.61E-19mmHg at 25°C |
| Appearance | White powder |
| pKa | 3?+-.0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.5500 (estimate) |
205526-36-9 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | 36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
205526-36-9 - Introduction
(S)-N-FMOC-3-Cyanophenylalanine is an organic compound with the following properties:
1. Appearance: usually white or yellow solid.
2. Solubility: Soluble in organic solvents such as dichloromethane, dimethylformamide, etc., insoluble in water.
3. Stability: relatively stable under regular storage conditions.
(S)-N-FMOC-3-Cyanophenylalanine are mainly used as protecting groups in peptide synthesis and solid phase synthesis. It can optionally add a Fmoc protecting group at the amino terminus to prevent the reaction of other functional groups, thereby controlling the position of peptide synthesis and reducing the generation of side reactions. In solid-phase synthesis, it is often used for peptide chain extension on solid-phase synthetic resins.
Its preparation method is generally obtained by chemical synthesis. The specific synthesis method may vary depending on the technique and conditions of the laboratory.
Safety precautions required when using and handling (S)-N-FMOC-3-Cyanophenylalanine:
1. Use personal protective equipment such as protective gloves, glasses, and laboratory goggles.
2. Avoid direct contact with skin and eyes, such as accidental contact, please immediately rinse with plenty of water for at least 15 minutes, and seek medical help.
3. Avoid inhaling dust and ensure that the operation is in a well-ventilated environment.
4. Storage should be sealed in a cool, dry, dark place, away from fire and oxidant.
Due to the variable nature of chemicals, if you need to use (S)-N-FMOC-3-Cyanophenylalanine, please refer to the relevant literature and operating manuals, and follow the safe operating procedures in the laboratory.
1. Appearance: usually white or yellow solid.
2. Solubility: Soluble in organic solvents such as dichloromethane, dimethylformamide, etc., insoluble in water.
3. Stability: relatively stable under regular storage conditions.
(S)-N-FMOC-3-Cyanophenylalanine are mainly used as protecting groups in peptide synthesis and solid phase synthesis. It can optionally add a Fmoc protecting group at the amino terminus to prevent the reaction of other functional groups, thereby controlling the position of peptide synthesis and reducing the generation of side reactions. In solid-phase synthesis, it is often used for peptide chain extension on solid-phase synthetic resins.
Its preparation method is generally obtained by chemical synthesis. The specific synthesis method may vary depending on the technique and conditions of the laboratory.
Safety precautions required when using and handling (S)-N-FMOC-3-Cyanophenylalanine:
1. Use personal protective equipment such as protective gloves, glasses, and laboratory goggles.
2. Avoid direct contact with skin and eyes, such as accidental contact, please immediately rinse with plenty of water for at least 15 minutes, and seek medical help.
3. Avoid inhaling dust and ensure that the operation is in a well-ventilated environment.
4. Storage should be sealed in a cool, dry, dark place, away from fire and oxidant.
Due to the variable nature of chemicals, if you need to use (S)-N-FMOC-3-Cyanophenylalanine, please refer to the relevant literature and operating manuals, and follow the safe operating procedures in the laboratory.
Last Update：2024-04-09 21:21:28
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