20628-06-2
2'-hydroxy-4',5'-dimethoxyacetophenone
CAS: 20628-06-2
Molecular Formula: C10H12O4
20628-06-2 - Names and Identifiers
20628-06-2 - Physico-chemical Properties
| Molecular Formula | C10H12O4 |
| Molar Mass | 196.2 |
| Density | 1.172±0.06 g/cm3(Predicted) |
| Melting Point | 113-114°C |
| Boling Point | 332.3±37.0 °C(Predicted) |
| Flash Point | 130.6°C |
| Vapor Presure | 7.63E-05mmHg at 25°C |
| Appearance | powder |
| Color | White to Light yellow to Light orange |
| pKa | 10.29±0.23(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.527 |
| MDL | MFCD00017241 |
20628-06-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
20628-06-2 - Introduction
2 '-hydroxy-4',5 '-dimethoxyacetophenone, chemical formula C10H12O4, molecular weight of 196.20g/mol. The following is its nature, use, preparation and safety information:
Nature:
2 '-hydroxy-4',5 '-dimethoxyacetophenone is an organic compound with colorless or yellowish crystal appearance. It is stable at room temperature and is not volatile. It has an aromatic odor and can be dissolved in some organic solvents such as ethanol and dimethylformamide.
Use:
2 '-hydroxy-4',5 '-dimethoxyacetophenone is commonly used as a drug intermediate, mainly for the synthesis of anti-inflammatory drugs, analgesic drugs and anti-allergic drugs. Because of its regulatory effect on inflammatory reaction and allergic reaction, it is widely used in the field of medicine.
Method:
2 '-hydroxy-4',5 '-dimethoxyacetophenone has various preparation methods. One commonly used method is the condensation reaction of acetanilide and methyl iodide under alkaline conditions, hydroxymethylation and methoxylation reactions are then carried out to give the target product.
Safety Information:
2 '-hydroxy-4',5 '-dimethoxyacetophenone needs to pay attention to safety protection measures in the use of scientific laboratories. It is irritating and may cause damage to the skin, eyes and respiratory system. Avoid direct contact with skin and eyes, and wear appropriate protective gloves and goggles when necessary. At the same time, the experimental site should be kept well ventilated to avoid inhaling the gas of the compound. Avoid contact with oxidants, acids and high temperatures during storage and handling. For safety reasons, the safe operation manual of the compound should be carefully understood before use, and the handling and storage should be carried out according to relevant regulations.
Nature:
2 '-hydroxy-4',5 '-dimethoxyacetophenone is an organic compound with colorless or yellowish crystal appearance. It is stable at room temperature and is not volatile. It has an aromatic odor and can be dissolved in some organic solvents such as ethanol and dimethylformamide.
Use:
2 '-hydroxy-4',5 '-dimethoxyacetophenone is commonly used as a drug intermediate, mainly for the synthesis of anti-inflammatory drugs, analgesic drugs and anti-allergic drugs. Because of its regulatory effect on inflammatory reaction and allergic reaction, it is widely used in the field of medicine.
Method:
2 '-hydroxy-4',5 '-dimethoxyacetophenone has various preparation methods. One commonly used method is the condensation reaction of acetanilide and methyl iodide under alkaline conditions, hydroxymethylation and methoxylation reactions are then carried out to give the target product.
Safety Information:
2 '-hydroxy-4',5 '-dimethoxyacetophenone needs to pay attention to safety protection measures in the use of scientific laboratories. It is irritating and may cause damage to the skin, eyes and respiratory system. Avoid direct contact with skin and eyes, and wear appropriate protective gloves and goggles when necessary. At the same time, the experimental site should be kept well ventilated to avoid inhaling the gas of the compound. Avoid contact with oxidants, acids and high temperatures during storage and handling. For safety reasons, the safe operation manual of the compound should be carefully understood before use, and the handling and storage should be carried out according to relevant regulations.
Last Update：2024-04-09 21:11:58
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