20712-16-7
5-chloro-3-methylpyridin-2-amine
CAS: 20712-16-7
Molecular Formula: C6H7ClN2
20712-16-7 - Names and Identifiers
20712-16-7 - Physico-chemical Properties
| Molecular Formula | C6H7ClN2 |
| Molar Mass | 142.59 |
| Density | 1.260 |
| Melting Point | 56-61°C |
| Boling Point | 254℃ |
| Flash Point | 107℃ |
| Vapor Presure | 0.0182mmHg at 25°C |
| pKa | 4.98±0.49(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.592 |
| MDL | MFCD00129030 |
20712-16-7 - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/39 - S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
20712-16-7 - Introduction
It is an organic compound with the chemical formula C7H8ClN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a white crystalline solid.
-Solubility: Its solubility in water is low, but it can be dissolved in organic solvents (such as ethanol and dimethylformamide).
-Stability: It is relatively stable at room temperature and can be decomposed under light or heating conditions.
Use:
It has a wide range of applications in the field of organic synthesis.
-It can be used as an intermediate for the synthesis of pyridine compounds and other organic compounds.
-In drug synthesis, it is often used as a synthetic raw material for Antibacterial Drugs and antiparasitic drugs.
Method:
It can be prepared by the following reaction:
-First, 3-picoline reacts with sodium chloride in the presence of sodium carbonate to produce 2-methyl-3-chloropyridine.
-Then, 2-methyl -3-chloropyridine reacts with ammonia in a carbonate buffer solution to generate a pyridine.
Safety Information:
-For the use and operation of chemicals, please refer to the Safety Data Sheet (MSDS) and appropriate operating specifications.
-May be irritating to skin, eyes and respiratory tract.
-When using, avoid inhaling aerosols or contact with skin and eyes.
-In the operation, should follow the appropriate safety measures, such as wearing protective gloves, safety glasses and protective masks.
Nature:
-Appearance: It is a white crystalline solid.
-Solubility: Its solubility in water is low, but it can be dissolved in organic solvents (such as ethanol and dimethylformamide).
-Stability: It is relatively stable at room temperature and can be decomposed under light or heating conditions.
Use:
It has a wide range of applications in the field of organic synthesis.
-It can be used as an intermediate for the synthesis of pyridine compounds and other organic compounds.
-In drug synthesis, it is often used as a synthetic raw material for Antibacterial Drugs and antiparasitic drugs.
Method:
It can be prepared by the following reaction:
-First, 3-picoline reacts with sodium chloride in the presence of sodium carbonate to produce 2-methyl-3-chloropyridine.
-Then, 2-methyl -3-chloropyridine reacts with ammonia in a carbonate buffer solution to generate a pyridine.
Safety Information:
-For the use and operation of chemicals, please refer to the Safety Data Sheet (MSDS) and appropriate operating specifications.
-May be irritating to skin, eyes and respiratory tract.
-When using, avoid inhaling aerosols or contact with skin and eyes.
-In the operation, should follow the appropriate safety measures, such as wearing protective gloves, safety glasses and protective masks.
Last Update：2024-04-09 21:01:54
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