208173-22-2
2,3,6-trifluoroacetophenone
CAS: 208173-22-2
Molecular Formula: C8H5F3O
208173-22-2 - Names and Identifiers
208173-22-2 - Physico-chemical Properties
| Molecular Formula | C8H5F3O |
| Molar Mass | 174.12 |
| Density | 1.303±0.06 g/cm3(Predicted) |
| Boling Point | 187.2±35.0 °C(Predicted) |
| Flash Point | 65°C |
| Vapor Presure | 0.637mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.467 |
| MDL | MFCD00070809 |
208173-22-2 - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 1224 |
| Hazard Note | Irritant/Flammable |
| Hazard Class | IRRITANT |
| Packing Group | III |
208173-22-2 - Introduction
2,3,6-trifluoroacetophenone, also known as trifluoroacetophenone, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 2,3,6-trifluoroacetophenone is a colorless liquid.
-Solubility: It is soluble in organic solvents such as ethanol, ether and chloroform, and insoluble in water.
-Melting point: About -20 ° C.
-Boiling point: about 105 ° C.
Use:
- 2,3,6-trifluoroacetophenone is widely used in the field of organic synthesis and is commonly used as a fluorination reagent for fluorine compounds.
-It is also used as a key raw material in the field of dyes, organic synthesis intermediates and pharmaceuticals.
Method:
2,3,6-trifluoroacetophenone can be prepared by the following methods:
-Fluorination reaction of aromatic compounds: The corresponding acetophenone is reacted with fluorine gas under appropriate catalyst and conditions, and the fluorination reaction is carried out in an appropriate solvent.
-Reaction of fluorination reagent: The fluorination reagent (such as boron trifluoride, lithium fluoride, etc.) is reacted with the corresponding aromatic substance, and then through appropriate steps to obtain 2,3,6-trifluoroacetophenone.
Safety Information:
- 2,3,6-trifluoroacetophenone is a chemical that should be used with caution.
-During use, appropriate protective measures need to be taken, such as wearing chemical protective gloves and goggles to ensure good ventilation conditions.
-Avoid inhalation, ingestion or contact with skin and eyes to avoid irritation and injury.
-During storage and handling, avoid contact with oxidants, strong acids or alkalis to prevent dangerous reactions.
Nature:
-Appearance: 2,3,6-trifluoroacetophenone is a colorless liquid.
-Solubility: It is soluble in organic solvents such as ethanol, ether and chloroform, and insoluble in water.
-Melting point: About -20 ° C.
-Boiling point: about 105 ° C.
Use:
- 2,3,6-trifluoroacetophenone is widely used in the field of organic synthesis and is commonly used as a fluorination reagent for fluorine compounds.
-It is also used as a key raw material in the field of dyes, organic synthesis intermediates and pharmaceuticals.
Method:
2,3,6-trifluoroacetophenone can be prepared by the following methods:
-Fluorination reaction of aromatic compounds: The corresponding acetophenone is reacted with fluorine gas under appropriate catalyst and conditions, and the fluorination reaction is carried out in an appropriate solvent.
-Reaction of fluorination reagent: The fluorination reagent (such as boron trifluoride, lithium fluoride, etc.) is reacted with the corresponding aromatic substance, and then through appropriate steps to obtain 2,3,6-trifluoroacetophenone.
Safety Information:
- 2,3,6-trifluoroacetophenone is a chemical that should be used with caution.
-During use, appropriate protective measures need to be taken, such as wearing chemical protective gloves and goggles to ensure good ventilation conditions.
-Avoid inhalation, ingestion or contact with skin and eyes to avoid irritation and injury.
-During storage and handling, avoid contact with oxidants, strong acids or alkalis to prevent dangerous reactions.
Last Update：2024-04-09 02:00:44
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