212378-89-7

212378-89-7 - Names and Identifiers

Name	(1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol
Synonyms	(1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-... (1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzylidene)amino]-2-indanol (1S,2R)-1-[(3,5-ditert-butyl-2-hydroxy-phenyl)methyleneamino]indan-2-ol (1S,2R)-1-((3,5-Di-tert-butyl-2-hydroxybenzylidene)amino)-2,3-dihydro-1H-inden-2-ol 1H-Inden-2-ol, 1-[[[3,5-bis(1,1-dimethylethyl)-2-hydroxyphenyl]methylene]amino]-2,3-dihydro-, (1S,2R)-
CAS	212378-89-7
InChI	InChI=1/C24H31NO2/c1-23(2,3)17-11-16(22(27)19(13-17)24(4,5)6)14-25-21-18-10-8-7-9-15(18)12-20(21)26/h7-11,13-14,20-21,26-27H,12H2,1-6H3/b25-14+/t20-,21+/m1/s1

212378-89-7 - Physico-chemical Properties

Molecular Formula	C24H31NO2
Molar Mass	365.51
Density	1.08g/cm³
Melting Point	128-131°C
Boling Point	496°C at 760 mmHg
Flash Point	330.3°C
Vapor Presure	1.18E-10mmHg at 25°C
Refractive Index	1.565

212378-89-7 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3

212378-89-7 - Introduction

(1S,2R)-1-[(3,) amino]-2-indanol, also known as (1S,2R)-1-[(3,5-Di-tert-butyl-2-hydroxybenzaldehyde)-2-indanol, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Molecular formula: C25H35NO2
-Molecular weight: 393.55g/mol
-Appearance: White crystalline solid
-Melting point: 138-140 ° C
-Storage conditions: Store in a cool, dry place, away from fire and oxidant

Use:
- (1S,2R)-1-[(3, 2R) amino]-2-indanol is a chiral ligand that can be used to catalyze asymmetric synthesis reactions.
-It also has certain applications in the field of medicine and can be used to synthesize drugs or drug intermediates.

Method:
- (1S,2R)-1-[(3, 2R) amino]-2-indanol preparation method is more complex, usually involving a multi-step reaction.
-A commonly used preparation method involves the reduction of a chiral ketone and an appropriate chiral reducing agent to obtain the desired chiral product.

Safety Information:
-In view of the structural activity of this compound and its use, safety measures need to be taken for handling.
-Keep away from ignition and oxidizing agents.
-Wear appropriate personal protective equipment, such as protective gloves and glasses, when operating.
-During use, care should be taken to avoid contact with the skin and inhalation of its dust or vapor.
-Observe all applicable safety rules and regulations during storage and handling.

Last Update：2024-04-09 02:00:44